Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195046 | 0.83 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL3208378 | 0.83 | CYP2D6 (0.45) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL7920376 | 0.82 | HTR1A (0.41) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4224731 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL730472 | 0.81 | PTGIR (0.46) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4621993 | 0.81 | CA2 (0.43) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4621704 | 0.81 | CA2 (0.43) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4962952 | 0.80 | LMNA (0.44) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL4960403 | 0.80 | LMNA (0.44) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL3205941 | 0.76 | NISCH (0.36) | GRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | ALDH1A1 1164/4885CYP3A4 298/4885CYP2D6 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.