SCHEMBL320849

SCHEMBL320849

Cc1ncnc2c1ncn2N

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 9/20 0.41
ADORA1 P30542 7/20 0.41
PI4KA P42356 8/20 0.38
PI4K2B Q8TCG2 8/20 0.38
PI4K2A Q9BTU6 8/20 0.38
PI4KB Q9UBF8 8/20 0.38
ADORA2B P29275 3/20 0.38
YTHDC1 Q96MU7 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33
AHCY P23526 2/20 0.33
EGFR P00533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL441875 0.77 ADORA1 (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL667204 0.77 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL15829723 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16949893 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL5490469 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16949944 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1868819 0.75 FDPS (0.44) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1193370 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28174152 0.75 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL23771392 0.75 YTHDC1 (0.66) ADORA2AADORA1ADORA2BYTHDC1AHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620599-B1 Inoculating plants in cultures and mixtures comprising auxins and cytokinins, then incubating, extracting in solvents and filtering to obtain flavonoids COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-09-16 US claimed
US-6365757-B1 CULTURING TISSUES OF TAXUS WALLICHIANIA; ISOLATION BY PARTITIONING THE CULTURE PRODUCT RESIDUE, OBTAINED BY POLAR SOLVENT EXTRACTION; DESOLVENTIZING BETWEEN WATER AND CHLORINATED SOLVENTS; EVAPORATION; CHROMOTOGRAPHY; ADSORPTION; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-02 US claimed
US-20250059537-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-02-20 US disclosed
EP-4448541-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE Oxford University Innovation Limited (GB) 2024-10-23 EP disclosed
WO-2023111597-A1 THERAPEUTIC OLIGONUCLEOTIDES HAVING AN INTER-NUCLEOSIDE AMIDE LINKAGE OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-06-22 WO disclosed
WO-2022268932-A1 SYSTEMS AND METHODS FOR SINGLE CELL ANALYSIS THERMO FISHER SCIENTIFIC GENEART GMBH (DE) 2022-12-29 WO disclosed
EP-3469009-B1 SOLID SUPPORT LIFE TECH AS (NO) 2022-04-13 EP disclosed
US-11041068-B2 Solid support LIFE TECHNOLOGIES AS (NO) 2021-06-22 US disclosed
EP-3613743-A1 PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES Intellikine, LLC (US) 2020-02-26 EP disclosed
US-20190264017-A1 SOLID SUPPORT LIFE TECHNOLOGIES AS (NO) 2019-08-29 US disclosed
EP-3469009-A1 SOLID SUPPORT Life Technologies AS (NO) 2019-04-17 EP disclosed
WO-2002083954-A1 MOBILITY-MODIFIED NUCLEOBASE POLYMERS AND METHODS OF USING SAME APPLERA CORPORATION (US) 2002-10-24 WO disclosed
WO-2002079516-A1 NUCLEIC ACID ANALYSIS USING NON-TEMPLATED NUCLEOTIDE ADDITION APPLERA CORPORATION (US) 2002-10-10 WO disclosed
US-20020142342-A1 Nucleic acid analysis using non-templated nucleotide addition PE CORPORATION (NY) (US) 2002-10-03 US disclosed
US-6365757-B1 CULTURING TISSUES OF TAXUS WALLICHIANIA; ISOLATION BY PARTITIONING THE CULTURE PRODUCT RESIDUE, OBTAINED BY POLAR SOLVENT EXTRACTION; DESOLVENTIZING BETWEEN WATER AND CHLORINATED SOLVENTS; EVAPORATION; CHROMOTOGRAPHY; ADSORPTION; COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-04-02 US disclosed
WO-2002010182-A2 METHODS FOR ISOLATING ONE STRAND OF A DOUBLE-STRANDED NUCLEIC ACID APPLERA CORPORATION (US) 2002-02-07 WO disclosed
EP-1148947-A1 FIBRE ARRAY FOR CONTACTING CHEMICAL SPECIES AND METHODS FOR USING AND MAKING SAME PE Corporation (NY) (US) 2001-10-31 EP disclosed
WO-2000040334-A1 FIBER ARRAY FOR CONTACTING CHEMICAL SPECIES AND METHODS FOR USING AND MAKING SAME PE CORPORATION (NY) (US) 2000-07-13 WO disclosed
WO-1999060170-A1 LINEAR ARRAYS OF IMMOBILIZED COMPOUNDS AND METHODS OF USING SAME HYSEQ, INC. (US) 1999-11-25 WO disclosed
EP-0052959-B1 PRODUCTION OF PURINE DERIVATIVES AND INTERMEDIATES THEREFOR Takeda Chemical Industries, Ltd. (JP) 1986-01-29 EP disclosed