Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13018082 | 0.84 | NOTUM (0.33) | KDM4EHCAR2DAOALDH1A1 | |
| SCHEMBL3709102 | 0.84 | PDPK1 (0.36) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL5361736 | 0.82 | — | — | |
| SCHEMBL21257121 | 0.82 | TSHR (0.33) | TSHRP4HA1P4HTMTP53ALOX15 | |
| SCHEMBL21257031 | 0.82 | TSHR (0.33) | TSHRP4HA1P4HTMTP53ALOX15 | |
| SCHEMBL1220609 | 0.78 | ALDH1A1 (0.47) | TSHRTP53KDM4ETDP1CA1 | |
| SCHEMBL21257118 | 0.78 | NPC1 (0.36) | TSHRP4HA1P4HTMTP53ALOX15 | |
| SCHEMBL14338421 | 0.78 | KMO (0.32) | DAO | |
| SCHEMBL11655407 | 0.77 | — | — | |
| SCHEMBL1146219 | 0.75 | TSHR (0.38) | TSHRTP53ALOX15NAPRTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | claimed |
| CN-117797875-A | Preparation method of zirconium-based metal organic framework-based photocatalytic material and light stability research method thereof | 中国科学技术大学 | 2024-04-02 | — | — | CN | claimed |
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118206560-A | Lipoic acid derivative containing pyridazino indole structure, and preparation method and application thereof | 浙江中医药大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-117797875-A | Preparation method of zirconium-based metal organic framework-based photocatalytic material and light stability research method thereof | 中国科学技术大学 | 2024-04-02 | — | — | CN | disclosed |
| EP-3562487-B1 | METALLOENZYME INHIBITOR COMPOUNDS | JI XING PHARMACEUTICALS HONG KONG LTD (HK) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023170174-A1 | METHOD FOR PROVIDING A LABELED SINGLE ISOMERIC CHEMICAL ENTITY TARGETING VECTOR BASED ON THE USE OF AN ISOMER-FREE DIENOPHILE | UNIVERSITY OF COPENHAGEN (DK) | 2023-09-14 | — | — | WO | disclosed |
| US-11325925-B2 | Dihydropyridazine antioxidant sunscreens | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-05-10 | — | — | US | disclosed |
| CN-110760030-B | Preparation method and application of hydrophobic material based on nanoparticles | 江苏慧智新材料科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10850258-B2 | Modified porous composite structure, method for manufacturing the same and method for absorbing organic liquid | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2020-12-01 | — | — | US | disclosed |
| US-10850258-B2 | Modified porous composite structure, method for manufacturing the same and method for absorbing organic liquid | CHUNG YUAN CHRISTIAN UNIVERSITY (TW) | 2020-12-01 | — | — | US | disclosed |
| CN-101925660-A | Organosilane coating composition and use thereof | DUBLIN INST OF TECHNOLOGY | 2010-12-22 | — | — | CN | disclosed |
| WO-2010081145-A1 | ANTI-VIRAL COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLAXOSMITHKLINE LLC (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100029655-A1 | Processes For The Preparation Of Anti-Viral Compounds And Compositions Containing Them | LEIVERS MARTIN ROBERT | 2010-02-04 | — | — | US | disclosed |
| WO-2010006096-A1 | PROCESSES FOR THE PREPARATION OF ANTI-VIRAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-14 | — | — | WO | disclosed |
| WO-2009069111-A2 | SOL-GEL COATING COMPOSITIONS AND THEIR PROCESS OF PREPARATION | DUBLIN INSTITUTE OF TECHNOLOGY (IE) | 2009-06-04 | — | — | WO | disclosed |
| EP-0014792-B1 | TETRAHYDRO-2H-BENZO(C)PYRROLES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THE COMPOUNDS FOR USE AS THERAPEUTICALS | ELI LILLY AND COMPANY (US) | 1982-12-01 | — | — | EP | disclosed |
| US-4264622-A | TREATMENT OF PARKINSON*S DISEASE | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4235776-A | USED FOR TREATMENT OF PARKINSON'S DISEASE, PROLACTIN INHIBITORS, AND DOPAMINE AGONISTS | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0014792-A1 | Tetrahydro-2H-benzo(c)pyrroles, their preparation, pharmaceutical compositions containing them and the compounds for use as therapeuticals | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11325925-B2 | Dihydropyridazine antioxidant sunscreens | QDPR, DLD, DPYD | TSHR 4867/4885P4HA1 208/4885P4HTM 264/4885 |
| US-20100029655-A1 | Processes For The Preparation Of Anti-Viral Compounds And Compositions Containing Them | RPL35, HAVCR2, RPL5 | TSHR 4860/4885P4HA1 2132/4885P4HTM 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.