⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321222 | 0.74 | MMP12 (0.35) | — | |
| SCHEMBL2319472 | 0.71 | ATP4A (0.39) | — | |
| SCHEMBL3159737 | 0.70 | DAO (0.47) | — | |
| SCHEMBL10404033 | 0.70 | — | — | |
| SCHEMBL15480266 | 0.70 | DAO (0.33) | — | |
| SCHEMBL1023821 | 0.65 | — | — | |
| SCHEMBL28942652 | 0.65 | — | — | |
| SCHEMBL2325532 | 0.64 | HDAC6 (0.43) | — | |
| SCHEMBL40746 | 0.64 | — | — | |
| SCHEMBL9773308 | 0.64 | DAO (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666866-B2 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 2010-02-23 | — | — | US | disclosed |
| EP-1819693-B1 | ANTITHROMBOTIC DIAMIDES | LILLY CO ELI (US) | 2009-08-26 | — | — | EP | disclosed |
| US-20090062271-A1 | Antithrombotic Diamides | ELI LILLY AND COMPANY (US) | 2009-03-05 | — | — | US | disclosed |
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | disclosed |
| EP-0436333-A2 | Azaoxindole derivatives | PFIZER INC. (US) | 1991-07-10 | — | — | EP | disclosed |
| US-4273573-A | Agents for regulating plant growth using 2-thiazolone-5-carboxylic acid compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |
| EP-0005204-A2 | Plant growth regulating compositions containing 2-thiazolon-5-carboxylic acid derivatives, their preparation and their application | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |