Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321222 | 0.80 | MMP12 (0.35) | HSD17B10NOTUMALDH1A1KMT2AAR | |
| SCHEMBL2325532 | 0.80 | HDAC6 (0.43) | NOTUMALDH1A1MEN1KMT2ADYRK1B | |
| SCHEMBL20288135 | 0.76 | HPGD (0.48) | ATP4AATP4BHSD17B10NOTUMACHE | |
| SCHEMBL2319480 | 0.74 | PGR (0.46) | ATP4AATP4BHSD17B10NOTUMACHE | |
| SCHEMBL28745195 | 0.73 | ACHE (0.50) | NOTUMACHEPTPN5ALDH1A1DHODH | |
| SCHEMBL29401977 | 0.73 | ACHE (0.50) | NOTUMACHEPTPN5ALDH1A1DHODH | |
| SCHEMBL8062082 | 0.73 | ACHE (0.50) | NOTUMACHEPTPN5ALDH1A1DHODH | |
| SCHEMBL160150 | 0.73 | ACHE (0.50) | NOTUMACHEPTPN5ALDH1A1DHODH | |
| SCHEMBL23773782 | 0.73 | ALDH1A1 (0.43) | ATP4AATP4BHSD17B10NOTUMACHE | |
| SCHEMBL12960188 | 0.73 | HSD17B10 (0.47) | ATP4AATP4BHSD17B10ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |