Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALAD | P13716 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320775 | 0.81 | BCL2L1 (0.35) | PGRARALDH1A1GAAMAPT | |
| SCHEMBL2319472 | 0.80 | ATP4A (0.39) | PGRARALDH1A1MAPTRAB9A | |
| SCHEMBL6451706 | 0.80 | NPC1 (0.42) | MMP12ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL2325532 | 0.80 | HDAC6 (0.43) | MMP12ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL3208771 | 0.74 | — | — | |
| SCHEMBL14198883 | 0.73 | ALDH1A1 (0.41) | MMP12ALDH1A1GAANPC1MAPT | |
| SCHEMBL2321226 | 0.71 | PGR (0.49) | MMP12PGRARALDH1A1GAA | |
| SCHEMBL14227569 | 0.69 | RAB9A (0.37) | MMP12ALDH1A1GAANPC1MAPT | |
| SCHEMBL1800477 | 0.68 | ALAD (0.69) | MMP12ALDH1A1GAARAB9AMCL1 | |
| SCHEMBL14817169 | 0.67 | TSHR (0.38) | MMP12ARALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |