Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30619865 | 0.86 | TRPA1 (0.55) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL2354241 | 0.84 | HSP90AA1 (0.60) | TRPA1PTGS1CACNA1CLMNAHSP90AA1 | |
| SCHEMBL29495445 | 0.84 | HSP90AA1 (0.60) | TRPA1PTGS1CACNA1CLMNAHSP90AA1 | |
| SCHEMBL12270315 | 0.84 | TRPA1 (0.48) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL14132618 | 0.84 | TRPA1 (0.53) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL1002950 | 0.82 | TRPA1 (0.52) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL13819748 | 0.82 | TRPA1 (0.47) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL28407092 | 0.81 | TRPA1 (0.50) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL17229430 | 0.80 | LMNA (0.47) | TRPA1PTGS1CACNA1CLMNABCHE | |
| SCHEMBL18944080 | 0.80 | PTGS1 (0.53) | TRPA1PTGS1CACNA1CLMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190010427-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2019-01-10 | — | — | US | claimed |
| JP-2131563-A | — | — | None | — | — | JP | disclosed |
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. | 2023-06-22 | — | — | US | disclosed |
| CN-109641814-B | Non-corrosive nitration inhibitor polar solvent preparation | 美国陶氏益农公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20190010427-A1 | SILICONE COMPOUNDS | THE PROCTER & GAMBLE COMPANY | 2019-01-10 | — | — | US | disclosed |
| EP-0941671-B1 | Taste agent from Saccharum Officinarum, process for preparing it, products containing it | INT FLAVORS & FRAGRANCES INC (US) | 2015-09-09 | — | — | EP | disclosed |
| US-7678752-B2 | Fabric care composition comprising organosilicone microemulsion and anionic/nitrogen-containing surfactant system | THE PROCTER & GAMBLE COMPANY (US) | 2010-03-16 | — | — | US | disclosed |
| EP-1313828-B2 | FABRIC CARE COMPOSITIONS COMPRISING CATIONIC SILICONES AND METHODS EMPLOYING SAME | PROCTER & GAMBLE (US) | 2009-10-14 | — | — | EP | disclosed |
| US-7384903-B2 | Fabric care and perfume compositions and systems comprising cationic silicones and methods employing same | THE PROCTER & GAMBLE COMPANY (US) | 2008-06-10 | — | — | US | disclosed |
| US-20070225198-A1 | Fabric care compositions and systems comprising organosilicone microemulsions and methods employing same | PROCTER & GAMBLE COMPANY, THE | 2007-09-27 | — | — | US | disclosed |
| US-4126569-A | Process of enhancing the aroma of a soap with liquid detergent norbornane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126641-A | KETAL, HYDROLYSIS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126570-A | Process of enhancing the aroma of a detergent with norbornane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4126571-A | Process of enhancing the aroma of a soap with norbornane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4123393-A | Substituted-norbornane perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-10-31 | — | — | US | disclosed |
| US-4120308-A | Substituted norbornane derivatives used in the process of flavoring tobacco and the product thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4119577-A | Substituted-norbornane perfumes compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4076853-A | Flavoring with substituted norbornane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4076854-A | ADJUVANTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-3936498-A | ALKANOYL ALKANOIC ACID OR SALT | OLIN CORPORATION (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192904-A1 | BIFUNCTIONAL CHIMERIC MOLECULES FOR LABELING OF KINASES WITH TARGET BINDING MOIETIES AND METHODS OF USE THEREOF | ERBB2, ACP1, TK1 | TRPA1 4664/4885PTGS1 3935/4885CACNA1C 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.