SCHEMBL32101

SCHEMBL32101

COC(C(=O)c1ccccc1)(C(=O)c1ccccc1)C(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.56
SRC P12931 1/20 0.52
TSHR P16473 3/20 0.47
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CES2 O00748 4/20 0.41
LMNA P02545 2/20 0.40
F2 P00734 1/20 0.40
ELANE P08246 2/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
KCNN4 O15554 1/20 0.38
POLB P06746 1/20 0.38
PRSS1 P07477 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28276721 0.86 CES1 (0.58) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL10324232 0.82 CES1 (0.50) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL27794375 0.82 CES1 (0.50) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL27980842 0.82 CES1 (0.50) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL28376869 0.80 PRSS1 (0.43) CES1SRCTSHRALDH1A1CES2
SCHEMBL27961634 0.79 CES1 (0.51) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL8332006 0.79 CES1 (0.60) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL10090157 0.79 CES1 (0.60) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL3661644 0.79 CES1 (0.60) CES1SRCTSHRTDP1ALDH1A1
SCHEMBL50469 0.78 CES1 (0.58) CES1SRCTSHRTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1069 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357485-B1 SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2026-05-27 EP claimed
US-20250339353-A1 A HIGH SPF GEL COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2025-11-06 US claimed
EP-4643846-A1 COSMETIC PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-05 EP claimed
US-20250186331-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-12 US claimed
EP-4558121-A1 FRAGRANCED COMPOSITION COMPRISING AT LEAST ONE SULFUR-COMPRISING ANTIOXIDANT COMPOUND, AT LEAST ONE ORGANIC UV SCREENING AGENT AND AT LEAST ONE FRAGRANCING SUBSTANCE L'OREAL (FR) 2025-05-28 EP claimed
EP-4395733-B1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B V (NL) 2025-04-30 EP claimed
CN-119677494-A Flavored composition comprising at least one sulfur-containing antioxidant compound, at least one organic UV screening agent and at least one flavoring substance 莱雅公司 2025-03-21 CN claimed
CN-115023218-B External preparation for skin 花王株式会社 2025-02-14 CN claimed
EP-4501311-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-02-05 EP claimed
WO-2025021553-A1 A PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2025-01-30 WO claimed
US-20100034893-A1 PARTICULATE UV PROTECTION AGENT MERCK PATENT GMBH (DE) 2010-02-11 US claimed
EP-1848507-B1 PREPARATION CONTAINING NANOPARTICULATE UV PROTECTION AGENTS MERCK PATENT GMBH (DE) 2009-08-05 EP claimed
EP-1848507-A1 PREPARATION CONTAINING NANOPARTICULATE UV PROTECTION AGENTS Merck Patent GmbH (DE) 2007-10-31 EP claimed
EP-1803435-A2 Cosmetic sun protection compositions based on lamelliform emulsions HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-07-04 EP claimed
US-20060194057-A1 Silicon dioxide-coated nanoparticulate uv protectant MERCK PATENT GMBH (DE) 2006-08-31 US claimed
WO-2006087066-A1 PREPARATION CONTAINING NANOPARTICULATE UV PROTECTION AGENTS MERCK PATENT GMBH (DE) 2006-08-24 WO claimed
EP-1660592-A1 SILICON DIOXIDE-COATED NANOPARTICULATE UV PROTECTANT MERCK PATENT GmbH (DE) 2006-05-31 EP claimed
CN-1744876-A Cosmetic composition UNILEVER HOME & PERSONAL CARE (NL) 2006-03-08 CN claimed
WO-2005019348-A1 SILICON DIOXIDE-COATED NANOPARTICULATE UV PROTECTANT MERCK PATENT GMBH (DE) 2005-03-03 WO claimed
WO-1993010753-A1 UVA-ABSORBING SUNSCREEN METAL COMPLEXES RICHARDSON-VICKS, INC. (US) 1993-06-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186331-A1 COSMETIC H1-2, H1-0, H1-3 CES1 827/4885SRC 3057/4885TSHR 812/4885
US-20100034893-A1 PARTICULATE UV PROTECTION AGENT SOD1, SOD3, UNG CES1 4742/4885SRC 4032/4885TSHR 3135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.