Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414914 | 0.94 | CYP2A6 (0.65) | TDP1PTPN11CYP2A6LCKCA1 | |
| SCHEMBL29365729 | 0.90 | PTPN11 (0.68) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL69025 | 0.90 | PTPN11 (0.68) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL8732524 | 0.88 | PTPN11 (0.66) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL9979782 | 0.86 | PTPN11 (0.64) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL811009 | 0.85 | PTPN11 (0.58) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL20718475 | 0.84 | LCK (0.60) | TDP1PTPN11CYP2A6LCKCA1 | |
| SCHEMBL709231 | 0.84 | LCK (0.62) | TDP1PTPN11LCKCA1CA2 | |
| SCHEMBL12734103 | 0.83 | KMT2A (0.56) | TDP1CYP2A6MAPTALDH1A1CYP1A2 | |
| SCHEMBL7744907 | 0.82 | PTPN11 (0.65) | PTPN11LCKCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281080-B2 | Quinoline-based compounds and methods of inhibiting CDK8/19 | UNIVERSITY OF SOUTH CAROLINA (US) | 2025-04-22 | — | — | US | disclosed |
| CN-118702566-A | Preparation method of 2-methyl-6-naphthoate and 2, 6-naphthalene dicarboxylic acid | 开滦能源化工股份有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-118702570-A | Method for preparing 2, 6-dimethyl naphthalene dicarboxylate | 安徽泰达新材料股份有限公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2024049929-A2 | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED | PANNEX THERAPEUTICS INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| CN-114773192-B | Method for continuously preparing 2, 6-dimethyl naphthalene dicarboxylate slices | 煤炭科学技术研究院有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-11674966-B2 | Kit and method for measuring measurement target substance in biological sample | FUJIFILM CORPORATION (JP) | 2023-06-13 | — | — | US | disclosed |
| CN-217661612-U | Recrystallization system for purifying dimethyl 2, 6-naphthalene dicarboxylate | 煤炭科学技术研究院有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-20210371390-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | Amydis, Inc. | 2021-12-02 | — | — | US | disclosed |
| US-20210276956-A1 | QUINOLINE-BASED COMPOUNDS AND METHODS OF INHIBITING CDK8/19 | UNIVERSITY OF SOUTH CAROLINA (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210276956-A1 | QUINOLINE-BASED COMPOUNDS AND METHODS OF INHIBITING CDK8/19 | UNIVERSITY OF SOUTH CAROLINA (US) | 2021-09-09 | — | — | US | disclosed |
| CN-1007492-B | TECHNOLOGY FOR RECIRCULATING USE OF CATALYST | IDEMITSU PETROCHEMICAL CO (JP) | 1990-04-11 | — | — | CN | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| CN-87104325-A | Catalyst circulation is used technology | — | 1988-07-06 | — | — | CN | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| EP-0073663-B1 | THROMBOXANE SYNTHETASE INHIBITORS, PROCESSES FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pfizer Limited (GB) | 1986-06-18 | — | — | EP | disclosed |
| US-4590200-A | NON-INHIBITION OF PROSTACYCLIN SYNTHETASE OR CYCLO-OXYGENASE | PFIZER INC. (US) | 1986-05-20 | — | — | US | disclosed |
| US-4496572-A | Benzo-fused thromboxane synthetase inhibitors | PFIZER INC. (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |
| EP-0073663-A2 | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them | Pfizer Limited (GB) | 1983-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371390-A1 | AMYLOID TARGETING AGENTS AND METHODS OF USING THE SAME | APP, CRYAA, APBA1 | TDP1 973/4885PTPN11 4666/4885CYP2A6 4136/4885 |
| US-11674966-B2 | Kit and method for measuring measurement target substance in biological sample | KIT, TACR2, TACR1 | TDP1 1985/4885PTPN11 4127/4885CYP2A6 1878/4885 |
| US-12281080-B2 | Quinoline-based compounds and methods of inhibiting CDK8/19 | CDK8, CDK9, CDK19 | TDP1 801/4885PTPN11 2880/4885CYP2A6 3184/4885 |
| US-20210276956-A1 | QUINOLINE-BASED COMPOUNDS AND METHODS OF INHIBITING CDK8/19 | CDK8, CDK9, CDK19 | TDP1 684/4885PTPN11 2657/4885CYP2A6 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.