Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213851 | 0.85 | MEN1 (0.46) | P2RX7TAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL3205712 | 0.81 | TAS1R3 (0.39) | P2RX7TAS1R3TAS1R1TAS1R2KMT2A | |
| SCHEMBL3210251 | 0.79 | MEN1 (0.48) | P2RX7KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL3208894 | 0.79 | ALDH1A1 (0.44) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL3219949 | 0.77 | ALDH1A1 (0.53) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL3221372 | 0.73 | ALDH1A1 (0.53) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL3210493 | 0.72 | ALDH1A1 (0.62) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL29563786 | 0.70 | HTT (0.65) | TAS1R3TAS1R1TAS1R2KMT2AALDH1A1 | |
| SCHEMBL11746761 | 0.68 | ALDH1A1 (0.64) | TAS1R3TAS1R1TAS1R2KMT2AMEN1 | |
| SCHEMBL3223116 | 0.68 | PDE10A (0.41) | P2RX7TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | claimed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | claimed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | P2RX7 1342/4885TAS1R3 816/4885TAS1R1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.