Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.51 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210493 | 0.94 | ALDH1A1 (0.62) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL11746761 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL3209924 | 0.80 | PDE10A (0.41) | ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1999696 | 0.80 | TRPV1 (0.44) | ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL3208894 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2 | |
| SCHEMBL3754302 | 0.79 | MTNR1A (0.59) | — | |
| SCHEMBL3213851 | 0.78 | MEN1 (0.46) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL9315497 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL3210262 | 0.77 | P2RX7 (0.42) | ALDH1A1TAS1R3TAS1R1TAS1R2EPHX2 | |
| SCHEMBL3219218 | 0.77 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | claimed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | claimed |
| US-7674827-B2 | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2043444-A1 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | BASF SE (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-1957447-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2008009881-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED. (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007060120-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | ALDH1A1 128/4885TAS1R3 816/4885TAS1R1 527/4885 |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | AHCYL1, AHCY, TST | ALDH1A1 2138/4885TAS1R3 108/4885TAS1R1 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.