Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.37 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350673 | 0.87 | AKR1C1 (0.55) | AKR1C1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL4219088 | 0.86 | OPRM1 (0.42) | OPRM1HDAC1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL373567 | 0.83 | AKR1C1 (0.68) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| SCHEMBL2817038 | 0.83 | AKR1C1 (0.68) | AKR1C1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL13456896 | 0.83 | AKR1C1 (0.62) | AKR1C1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL378896 | 0.82 | APP (0.50) | AKR1C1OPRM1HDAC1KMT2AMEN1 | |
| SCHEMBL3032228 | 0.82 | AKR1C1 (0.47) | AKR1C1OPRM1HDAC1KMT2AMEN1 | |
| SCHEMBL4005636 | 0.82 | DRD2 (0.58) | AKR1C1OPRM1KMT2ATET3FBXL19 | |
| SCHEMBL6498800 | 0.82 | OPRM1 (0.53) | AKR1C1OPRM1HDAC1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL3210975 | 0.81 | AKR1C1 (0.66) | AKR1C1OPRM1HDAC1KMT2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048908-A1 | Process for Remifentanil Synthesis | MALLINCKRODT INC. | 2010-02-25 | — | — | US | disclosed |
| EP-2125730-A2 | NEW PROCESS FOR REMIFENTANIL SYNTHESIS | Mallinckrodt Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008066708-A2 | NEW PROCESS FOR REMIFENTANIL SYNTHESIS | MALLINCKRODT INC. (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048908-A1 | Process for Remifentanil Synthesis | OPRM1, OPRL1, OPRK1 | AKR1C1 2258/4885OPRM1 1/4885HDAC1 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.