Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.50 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.50 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3210975 | 0.98 | AKR1C1 (0.66) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| Hydrochloric Acid SCHEMBL18281540 | 0.98 | AKR1C1 (0.66) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| Hydrochloric Acid SCHEMBL2552731 | 0.98 | AKR1C1 (0.66) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| Formamide SCHEMBL27414478 | 0.90 | AKR1C1 (0.56) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| SCHEMBL4003991 | 0.89 | AKR1C1 (0.58) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| SCHEMBL28066667 | 0.89 | AKR1C1 (0.58) | AKR1C1OPRM1HDAC1KMT2ATET3 | |
| SCHEMBL31016196 | 0.85 | AKR1C1 (0.83) | AKR1C1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL6391 | 0.85 | AKR1C1 (0.83) | AKR1C1KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL476403 | 0.85 | OPRM1 (0.58) | AKR1C1OPRM1HDAC1TACR1HTR2A | |
| SCHEMBL38041 | 0.85 | OPRM1 (0.62) | AKR1C1OPRM1HDAC1TACR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | claimed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | claimed |
| CN-118515899-A | Acid-doped cross-linked polymer proton exchange membrane material and preparation method thereof | 西昌学院 | 2024-08-20 | — | — | CN | claimed |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2023-04-13 | — | — | US | claimed |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2022-11-24 | — | — | US | claimed |
| EP-2068878-A2 | RHO KINASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2009-06-17 | — | — | EP | claimed |
| EP-1670787-A4 | CYTOKINE INHIBITORS | KEMIA INC (US) | 2009-04-22 | — | — | EP | claimed |
| US-20080275029-A1 | Compounds for Treating Protein-Kinase Mediated Disorders | ASTEX THERAPEUTICS LIMITED (GB) | 2008-11-06 | — | — | US | claimed |
| US-20080161297-A1 | e.g. N-(7-Chloro-1-oxo-1,2-dihydro-isoquinolin-6-yl)-2-dimethylamino-2-phenyl-acetamide; hypertension, atherosclerosis, restenosis, stroke, heart failure, coronary vasospasm, cerebral vasospasm, ischemia/reperfusion injury, pulmonary hypertension, angina, myocardial infarction, | ALCON INC. (CH) | 2008-07-03 | — | — | US | claimed |
| WO-2008036540-A2 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-27 | — | — | WO | claimed |
| WO-2004063212-A2 | ORGANIC COMPOUNDS WITH BIOLOGICAL ACTION AS THROMBIN INHIBITORS AND USE THEROF | CPI CREATIVE PHARMA INTERNATIONAL GMBH (DE) | 2004-07-29 | — | — | WO | claimed |
| EP-1425296-A1 | ORGANIC COMPOUNDS WITH BIOLOGICAL ACTIVITY AS THROMBIN INHIBITORS AND USE THEREOF | Novel Science International Gmbh (DE) | 2004-06-09 | — | — | EP | claimed |
| WO-2003022873-A9 | ORGANIC COMPOUNDS WITH BIOLOGICAL ACTIVITY AS THROMBIN INHIBITORS AND USE THEREOF | NOVEL SCIENCE INTERNAT GMBH (DE) | 2003-12-11 | — | — | WO | claimed |
| WO-2003074055-A1 | PHARMACEUTICAL COMPOSITION OF A PDE4 OR A PDE3/4 INHIBITOR AND A HISTAMINE RECEPTOR ANTAGONIST | ALTANA PHARMA AG (DE) | 2003-09-12 | — | — | WO | claimed |
| US-20030092609-A1 | Novel antiarrythmic peptides | ZEALAND PHARMA A/S (DK) | 2003-05-15 | — | — | US | claimed |
| WO-2003022873-A1 | ORGANIC COMPOUNDS WITH BIOLOGICAL ACTIVITY AS THROMBIN INHIBITORS AND USE THEREOF | NOVEL SCIENCE INTERNATIONAL GMBH (DE) | 2003-03-20 | — | — | WO | claimed |
| EP-1226160-A2 | NOVEL ANTIARRHYTHMIC PEPTIDES | Zealand Pharmaceuticals A/S (DK) | 2002-07-31 | — | — | EP | claimed |
| WO-2001062775-A2 | NOVEL ANTIARRHYTHMIC PEPTIDES | ZEALAND PHARMA A/S (DK) | 2001-08-30 | — | — | WO | claimed |
| US-4045442-A | ANTIINFLAMMATORY, ANTIDIARRHEA | G. D. SEARLE & CO. (US) | 1977-08-30 | — | — | US | claimed |
| US-4017491-A | 1,1-Diaryl-1H-tetrazole amines | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | AKR1C1 4467/4885OPRM1 1752/4885HDAC1 1680/4885 |
| US-20080275029-A1 | Compounds for Treating Protein-Kinase Mediated Disorders | CNKSR1, PRKCH, PRKAR2B | AKR1C1 2208/4885OPRM1 1237/4885HDAC1 1192/4885 |
| US-20230111252-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | AKR1C1 2811/4885OPRM1 3052/4885HDAC1 547/4885 |
| US-20220372022-A1 | COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, NPEPPS, PAM | AKR1C1 4467/4885OPRM1 1752/4885HDAC1 1680/4885 |
| US-20030092609-A1 | Novel antiarrythmic peptides | TNNI3, TNNT2, TNNC1 | AKR1C1 4445/4885OPRM1 1188/4885HDAC1 4577/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | AKR1C1 2485/4885OPRM1 780/4885HDAC1 1231/4885 |
| US-20080161297-A1 | e.g. N-(7-Chloro-1-oxo-1,2-dihydro-isoquinolin-6-yl)-2-dimethylamino-2-phenyl-acetamide; hypertension, atherosclerosis, restenosis, stroke, heart failure, coronary vasospasm, cerebral vasospasm, ischemia/reperfusion injury, pulmonary hypertension, angina, myocardial infarction, | ROCK1, ROCK2, ARHGDIA | AKR1C1 1317/4885OPRM1 1596/4885HDAC1 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.