Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | FHIT | P49789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11108092 | 0.98 | ALDH1A1 (0.50) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3220413 | 0.87 | ALDH1A1 (0.50) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3219948 | 0.87 | HSP90AA1 (0.48) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL11109077 | 0.85 | ALDH1A1 (0.48) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3218276 | 0.84 | ALDH1A1 (0.50) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3199571 | 0.84 | KDM4E (0.43) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL11107107 | 0.83 | KDM4E (0.42) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL3084169 | 0.80 | GABRP (0.40) | GAAMAPK1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11113821 | 0.80 | CA12 (0.39) | MAPK1ALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL13014586 | 0.79 | ALDH1A1 (0.49) | GAAMAPK1ALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7091158-B2 | Substituted thienyl(amino)sulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| US-20050124496-A1 | Substituted thienyl(amino)sulphonylureas | GESING ERNST RUDOLF F (DE) | 2005-06-09 | — | — | US | disclosed |
| US-6887831-B1 | Substituted thienyl(amino)sulfonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| US-4428963-A | ANTILIPEMIC, ANTIOBESITY | HOFFMANN-LA ROCHE INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4317915-A | ANTILIPEMIC, ANTIOBESITY | HOFFMANN-LA ROCHE INC. (US) | 1982-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | GAA 3868/4885MAPK1 3267/4885ALDH1A1 975/4885 |
| US-20050124496-A1 | Substituted thienyl(amino)sulphonylureas | TST, DDT, SULT1E1 | GAA 2662/4885MAPK1 3787/4885ALDH1A1 419/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | GAA 3039/4885MAPK1 3327/4885ALDH1A1 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.