Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227327 | 0.82 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL3225580 | 0.82 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3NOS3NOS1 | |
| SCHEMBL3211442 | 0.76 | HTR1D (0.46) | SLC6A4HTR1DHTR1AHTR1E | |
| SCHEMBL7951141 | 0.74 | HTR1D (0.41) | HTR1DHTR1AHTR1E | |
| SCHEMBL3653965 | 0.74 | HTR1D (0.41) | SLC6A4HTR1DHTR1AHTR1E | |
| SCHEMBL3661903 | 0.73 | HTR1D (0.44) | SLC6A4SLC6A2NOS3NOS1HTR1D | |
| SCHEMBL3214861 | 0.73 | JAK3 (0.39) | HTR1DHTR1AHTR1E | |
| SCHEMBL3214716 | 0.73 | NOS3 (0.46) | SLC6A4SLC6A2NOS3NOS1HTR1D | |
| SCHEMBL3217678 | 0.72 | CDK7 (0.45) | HTR1DHTR1AHTR1E | |
| SCHEMBL3225505 | 0.69 | JAK2 (0.46) | HTR1DCYP2C19HTR1AHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056491-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056491-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR4, HTR3B | SLC6A4 24/4885SLC6A2 132/4885SLC6A3 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.