Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496436 | 0.75 | TRPA1 (0.47) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL9325711 | 0.74 | TRPA1 (0.50) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL185170 | 0.72 | TRPA1 (0.50) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL22206809 | 0.72 | TRPA1 (0.48) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL21331657 | 0.72 | TRPA1 (0.50) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL9719434 | 0.70 | TRPA1 (0.47) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL10012903 | 0.70 | TRPA1 (0.47) | TRPA1TAAR1MIFCYP2D6ADRA2C | |
| SCHEMBL7808281 | 0.70 | TRPA1 (0.47) | TRPA1TAAR1CYP2D6ADRA2CTSHR | |
| SCHEMBL1462504 | 0.70 | TRPA1 (0.47) | TRPA1TAAR1ADRA2CHTR2AADRA2A | |
| SCHEMBL1462503 | 0.70 | TRPA1 (0.47) | TRPA1TAAR1ADRA2CHTR2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | TRPA1 567/4885TAAR1 52/4885MIF 4320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.