Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43959 | 0.84 | TSHR (0.39) | TSHRLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL17595174 | 0.83 | TSHR (0.38) | TSHRLMNARAB9ASMN1; SMN2 | |
| Hydroxyamine SCHEMBL3213770 | 0.81 | TSHR (0.37) | TSHRKDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL2352790 | 0.74 | TSHR (0.31) | TSHRRAB9ASMN1; SMN2 | |
| Edetic Acid SCHEMBL3846372 | 0.71 | TDP1 (0.56) | TDP1EYA2APPACETSHR | |
| SCHEMBL4381249 | 0.70 | TSHR (0.38) | TSHRLMNARAB9ASMN1; SMN2 | |
| SCHEMBL2634577 | 0.68 | SMN1; SMN2 (0.40) | TSHRKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL121100 | 0.66 | TSHR (0.40) | TSHRLMNACYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL236431 | 0.66 | TSHR (0.56) | TSHRLMNARAB9ASMN1; SMN2 | |
| Edetic Acid SCHEMBL247531 | 0.66 | TDP1 (0.82) | TDP1EYA2APPACETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147230-A1 | METHOD FOR CONTROLLING THE EXTENSION OF AN OLIGONUCLEOTIDE | Aventis Pharmaceuticals, Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043544-A1 | METHOD FOR CONTROLLING THE EXTENSION OF AN OLIGONUCLEOTIDE | DADE BEHRING INC. (US) | 2000-07-27 | — | — | WO | disclosed |