Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43959 | 0.82 | TSHR (0.39) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17595174 | 0.81 | TSHR (0.38) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| Hydroxyamine SCHEMBL3213770 | 0.79 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL16841649 | 0.75 | TSHR (0.42) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL4381244 | 0.75 | KMT2A (0.36) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL2352790 | 0.73 | TSHR (0.31) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL5088057 | 0.72 | TSHR (0.37) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL2423505 | 0.71 | — | — | |
| SCHEMBL5091798 | 0.70 | TSHR (0.44) | TSHRSMN1; SMN2RAB9AMEN1KMT2A | |
| Edetic Acid SCHEMBL7787575 | 0.70 | TDP1 (0.40) | TSHRSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103429269-B | Contain with the coupling of polyanion polypeptide, derived from the conjugated molecule that is used for the treatment of AIDS of the peptide of CD4 acceptor | INSTITUT PASTEUR (FR) | 2016-05-11 | — | — | CN | disclosed |
| CN-104781281-A | Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin | ANGIOCHEM INC | 2015-07-15 | — | — | CN | disclosed |
| CN-102065884-B | Pegylated insulin lispro compounds | LILLY CO ELI | 2014-11-05 | — | — | CN | disclosed |
| CN-103561773-A | Theranostic imaging agents and methods of use | UNIV JOHNS HOPKINS | 2014-02-05 | — | — | CN | disclosed |
| CN-1901934-B | Use of erythropoietin in the treatment of disturbances of iron distribution in chronic inflammatory bowel disease | HOFFMANN LA ROCHE | 2013-09-11 | — | — | CN | disclosed |
| CN-102781965-A | Compositions and methods for the transport of therapeutic agents | ANGIOCHEM INC | 2012-11-14 | — | — | CN | disclosed |
| CN-102038955-B | Method for preparing anticoagulant polysulfone material by Friedel-crafts reaction grafting | Central South University Xiangya School of Medicine | 2012-04-18 | — | — | CN | disclosed |
| CN-102065884-A | Pegylated insulin lispro compounds | LILLY CO ELI | 2011-05-18 | — | — | CN | disclosed |
| CN-102038955-A | Method for preparing anticoagulant polysulfone material by Friedel-crafts reaction grafting | XIANGYA HOSPITAL CENTRAL SOUTH UNIV | 2011-05-04 | — | — | CN | disclosed |
| CN-102046203-A | Conjugated molecules comprising a peptide derived from the CD4 receptor coupled to a polyanion for the treatment of aids | PASTEUR INSTITUT | 2011-05-04 | — | — | CN | disclosed |
| US-7629295-B2 | Determination of a specific immunoglobulin using multiple antigens | ROCHE DIAGNOSTICS GMBH (DE) | 2009-12-08 | — | — | US | disclosed |
| CN-101421297-A | Peptides that block the binding of igg to fcrn | SYNTONIX PHARMACEUTICALS INC (US) | 2009-04-29 | — | — | CN | disclosed |
| CN-1309416-C | Novel pharmaceutical composition | HOFFMANN LA ROCHE (CH) | 2007-04-11 | — | — | CN | disclosed |
| CN-1901934-A | Use of erythropoietin in the treatment of disturbances of iron distribution in chronic inflammatory bowel disease | HOFFMANN LA ROCHE (CH) | 2007-01-24 | — | — | CN | disclosed |
| US-20050074750-A1 | Determination of a specific immunoglobulin using multiple antigens | WIENHUES URSULA-HENRIKE (DE) | 2005-04-07 | — | — | US | disclosed |
| US-6613530-B1 | Epitopes; antibodies; amino acid sequences; haptens; genetic engineering; chelate compounds; biotin; carriers; use in detection of HIV or Hepatitis C-virus antibodies in liquid sample incubated in presence of solid phase and two antigens | ROCHE DIAGNOSTICS GMBH (DE) | 2003-09-02 | — | — | US | disclosed |
| CN-1429116-A | Novel pharmaceutical composition | HOFFMANN LA ROCHE (CH) | 2003-07-09 | — | — | CN | disclosed |
| CN-1102594-C | Agent for suppressing interference in immuno assaying | ROCHE DIAGNOSTICS GMBH (DE) | 2003-03-05 | — | — | CN | disclosed |
| CN-1143368-A | Agent for suppressing interference in immuno assaying | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-19 | — | — | CN | disclosed |