SCHEMBL32144372

SCHEMBL32144372

N#Cc1cccc(C#CCO)c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.47
ENPP2 Q13822 1/20 0.46
GSK3B P49841 1/20 0.43
GRM5 P41594 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MELK Q14680 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82303 1.00 FFAR1 (0.47) FFAR1ENPP2GSK3BGRM5ALDH1A1
SCHEMBL5633251 0.89 ALDH1A1 (0.47) FFAR1GRM5ALDH1A1MELK
SCHEMBL24300824 0.85 ASIC3 (0.48) FFAR1ENPP2GSK3BGRM5
SCHEMBL30873480 0.80 GRM5 (0.55) FFAR1ENPP2GRM5
SCHEMBL29186210 0.80 GSK3B (0.47) FFAR1ENPP2GSK3BGRM5
SCHEMBL7050853 0.80 ALDH1A1 (0.41) FFAR1ALDH1A1MELK
SCHEMBL30866195 0.80 GSK3B (0.47) FFAR1ENPP2GSK3BGRM5
SCHEMBL24358854 0.80 FFAR1 (0.44) FFAR1ENPP2GSK3BGRM5
SCHEMBL30536352 0.80 FFAR1 (0.44) FFAR1ENPP2GSK3BGRM5
SCHEMBL78831 0.79 CA2 (0.48) ENPP2GSK3BALDH1A1MELK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4685143-A1 DOUBLE REGULATOR FOR MGLUR5 AND HDAC6 AND USE THEREOF Vivozon,Inc. (KR) 2026-01-28 EP disclosed