Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13487009 | 0.81 | IRAK4 (0.36) | NLRP3CYP2C9L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL3204829 | 0.81 | FFAR1 (0.38) | CYP2C9USP2FFAR1CYP2B6SLCO1B3 | |
| SCHEMBL3203094 | 0.71 | AKR1B1 (0.39) | NLRP3CYP2C9CYP3A4CYP2D6THRB | |
| SCHEMBL13487013 | 0.71 | IRAK4 (0.38) | NLRP3CYP2C9L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7612411 | 0.70 | MAPT (0.33) | NLRP3L3MBTL1ALDH1A1GAA | |
| SCHEMBL3207386 | 0.70 | IRAK4 (0.46) | CYP2C9L3MBTL1CYP3A4CYP2D6THRB | |
| SCHEMBL3220844 | 0.69 | CA2 (0.31) | — | |
| SCHEMBL13219199 | 0.69 | IRAK4 (0.43) | NLRP3CYP2C9CYP3A4CYP2D6THRB | |
| SCHEMBL5530352 | 0.68 | NLRP3 (0.35) | NLRP3CYP2C9CYP3A4CYP2D6THRB | |
| SCHEMBL13487012 | 0.68 | RAB9A (0.38) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
| WO-2008052075-A2 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | MAOB 160/4885NLRP3 512/4885CYP2C9 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.