Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3122772 | 0.93 | HDAC6 (0.39) | HDAC6RXRAPDE4DTRPM8PDE4B | |
| SCHEMBL3201201 | 0.93 | HRH4 (0.36) | HDAC6PDE4DLMNATRPM8CTSL | |
| SCHEMBL3203001 | 0.90 | POLB (0.35) | HDAC6PDE4DPDE4BCTSLPDE4A | |
| SCHEMBL3129699 | 0.90 | RXRA (0.42) | RXRAPDE4DLMNATP53PDE4B | |
| SCHEMBL3122650 | 0.89 | SLC7A5 (0.32) | HDAC6RXRAPDE4DLMNAPDE4B | |
| SCHEMBL3123577 | 0.88 | CTSL (0.35) | HDAC6PDE4DLMNAPDE4BCTSL | |
| SCHEMBL3120772 | 0.87 | GRM2 (0.38) | RXRAPDE4DLMNAPDE4BPDE4A | |
| SCHEMBL3201568 | 0.87 | GRM2 (0.40) | PDE4DLMNAPDE4BPDE4APDE4C | |
| SCHEMBL3125802 | 0.86 | RAB9A (0.39) | HDAC6RXRAPDE4DLMNATRPM8 | |
| SCHEMBL3133400 | 0.85 | PDE4D (0.41) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | HDAC6 329/4885RXRA 2856/4885PDE4D 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.