Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.39 |
| ▸ | CA12 | O43570 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 10/20 | 0.39 |
| ▸ | CA9 | Q16790 | 10/20 | 0.39 |
| ▸ | CA7 | P43166 | 6/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224221 | 0.89 | CA2 (0.38) | CA2CA12CA1CA9CA7 | |
| SCHEMBL3207237 | 0.86 | CA12 (0.35) | CA2CA12CA1CA9CA7 | |
| SCHEMBL3217589 | 0.84 | CA2 (0.44) | CA2CA12CA1CA9CA14 | |
| SCHEMBL3205561 | 0.82 | CA1 (0.44) | CA2CA12CA1CA9CA7 | |
| SCHEMBL3215200 | 0.82 | CA12 (0.41) | CA2CA12CA1CA9CA7 | |
| SCHEMBL3223422 | 0.81 | CA1 (0.40) | CA2CA12CA1CA9CA7 | |
| SCHEMBL13014576 | 0.80 | CYP2C9 (0.33) | CA2CA12CA1CA9CA7 | |
| SCHEMBL27461642 | 0.80 | CA2 (0.41) | CA2CA12CA1CA9CA7 | |
| SCHEMBL3209688 | 0.80 | ALDH1A1 (0.45) | CA2CA12CA1CA9ALDH1A1 | |
| SCHEMBL11113821 | 0.79 | CA12 (0.39) | CA2CA12CA1CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-7091158-B2 | Substituted thienyl(amino)sulphonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 2006-08-15 | — | — | US | disclosed |
| EP-1598351-A1 | Substituted N-pyrimidinyl-N'-thienyl(amino)sulfonylureas as herbicides | Bayer CropScience AG (DE) | 2005-11-23 | — | — | EP | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| EP-1206468-B1 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2005-06-15 | — | — | EP | disclosed |
| US-6887831-B1 | Substituted thienyl(amino)sulfonylureas | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-03 | — | — | US | disclosed |
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| CN-1137119-C | Substituted thineyl (amino) sulfonylureas | — | 2004-02-04 | — | — | CN | disclosed |
| CN-1368971-A | Substituted thineyl (amino) sulfonylureas | BAYER AG (DE) | 2002-09-11 | — | — | CN | disclosed |
| EP-1206468-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010863-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | CA2 2713/4885CA12 2976/4885CA1 3440/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | CA2 1297/4885CA12 3954/4885CA1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.