SCHEMBL3217545

SCHEMBL3217545

Cc1ccccc1CC(C)([Po])c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.39
SSTR4 P31391 1/20 0.35
NR3C2 P08235 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
CTBP2 P56545 1/20 0.35
MAPK1 P28482 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CHRM2 P08172 1/20 0.34
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
RIPK1 Q13546 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2008111 0.77 TAAR1 (0.39) TAAR1SSTR4NR3C2ALDH1A1HPGD
SCHEMBL808983 0.75 TAAR1 (0.45) TAAR1SSTR4NR3C2ALDH1A1HPGD
SCHEMBL3167835 0.74 RIPK1 (0.48) TAAR1SSTR4NR3C2ALDH1A1HPGD
SCHEMBL28114102 0.74 MEN1 (0.44) TAAR1NR3C2ALDH1A1HPGDCTBP2
SCHEMBL3217541 0.73 KIF11 (0.44) TAAR1ALDH1A1MAPK1SLC6A2KMT2A
SCHEMBL29877498 0.73 TAAR1 (0.37) TAAR1SSTR4NR3C2ALDH1A1HPGD
SCHEMBL8695221 0.73 HTT (0.43) SSTR4NR3C2ALDH1A1HPGDCTBP2
SCHEMBL10360565 0.72 TAAR1 (0.38) TAAR1ALDH1A1HPGDCTBP2CHRM2
SCHEMBL13722854 0.71 TAAR1 (0.45) TAAR1SSTR4NR3C2ALDH1A1HPGD
SCHEMBL15976426 0.71 TAAR1 (0.45) TAAR1SSTR4NR3C2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9499578-B2 Massively parallel synthesis of biopolymeric arrays INTEL CORPORATION (US) 2016-11-22 US disclosed
US-20100035771-A1 Molecular microarrays and helical peptides CABEZAS EDELMIRA 2010-02-11 US disclosed
US-7622295-B2 Molecular microarrays and helical peptides INTEL CORPORATION 2009-11-24 US disclosed
US-20090258796-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS RAJASEKARAN JOHN J 2009-10-15 US disclosed
US-20080318808-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS RAJASEKARAN JOHN J 2008-12-25 US disclosed
EP-1966230-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS Intel Corporation (US) 2008-09-10 EP disclosed
WO-2008097370-A2 METHOD FOR HIGH THROUGHPUT, HIGH VOLUME MANUFACTURING OF BIOMOLECULE MICRO ARRAYS INTEL CORPORATION (US) 2008-08-14 WO disclosed
US-20080145862-A1 Molecular microarrays and helical peptides INTEL CORPORATION 2008-06-19 US disclosed
WO-2007078868-A1 MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS INTEL CORPORATION (US) 2007-07-12 WO disclosed
US-20070154946-A1 Massively parallel synthesis of biopolymeric arrays INTEL CORPORATION 2007-07-05 US disclosed
US-20070122842-A1 Massively parallel synthesis of proteinaceous biomolecules INTEL CORPORATION 2007-05-31 US disclosed
US-20070122841-A1 Massively parallel synthesis of proteinaceous biomolecules INTEL CORPORATION 2007-05-31 US disclosed