Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215200 | 0.85 | CA12 (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3200213 | 0.84 | NPC1 (0.38) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3215781 | 0.83 | MAPT (0.41) | CA1CA2CA9MAPTPOLB | |
| SCHEMBL27552037 | 0.82 | CA12 (0.38) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3207237 | 0.82 | CA12 (0.35) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3209917 | 0.80 | CA12 (0.33) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3218236 | 0.80 | TSHR (0.43) | CA12CA1CA2CA9CA7 | |
| SCHEMBL3222126 | 0.77 | ALDH1A1 (0.45) | CA12CA1CA2CA9MAPT | |
| SCHEMBL7030429 | 0.76 | ALDH1A1 (0.38) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7033378 | 0.73 | NPC1 (0.49) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | CA12 2976/4885CA1 3440/4885CA2 2713/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | CA12 3954/4885CA1 3277/4885CA2 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.