Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | DDX3X | O00571 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | SCN4A | P35499 | 1/20 | 0.55 |
| ▸ | MC3R | P41968 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220378 | 0.87 | ALDH1A1 (0.51) | ALDH1A1DDX3XMAPTLMNACYP3A4 | |
| SCHEMBL3223733 | 0.87 | ALDH1A1 (0.55) | ALDH1A1DDX3XMAPTLMNAHDAC3 | |
| SCHEMBL2337206 | 0.84 | ALDH1A1 (0.60) | ALDH1A1DDX3XMAPTLMNAHDAC3 | |
| SCHEMBL14587039 | 0.84 | ALDH1A1 (0.60) | ALDH1A1DDX3XMAPTLMNAHDAC3 | |
| SCHEMBL397243 | 0.82 | POLB (0.67) | ALDH1A1DDX3XMAPTLMNACYP3A4 | |
| SCHEMBL3197036 | 0.81 | ALDH1A1 (0.53) | ALDH1A1DDX3XMAPTLMNAHDAC3 | |
| SCHEMBL6325836 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNACYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL8392614 | 0.81 | POLB (0.65) | ALDH1A1DDX3XMAPTLMNACYP3A4 | |
| SCHEMBL8623174 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNACYP3A4MAPK1 | |
| SCHEMBL78475 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145377-B2 | G-quadruplex stabilising agent | UNIVERSITY COLLEGE LONDON (GB) | 2015-09-29 | — | — | US | disclosed |
| US-9145377-B2 | G-quadruplex stabilising agent | UNIVERSITY COLLEGE LONDON (GB) | 2015-09-29 | — | — | US | disclosed |
| US-9145377-B2 | G-quadruplex stabilising agent | UNIVERSITY COLLEGE LONDON (GB) | 2015-09-29 | — | — | US | disclosed |
| EP-2694487-B1 | G-quadruplex stabilising agent | UNIV LONDON (GB) | 2015-09-16 | — | — | EP | disclosed |
| EP-2694487-B1 | G-quadruplex stabilising agent | UNIV LONDON (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-20140107168-A1 | G-QUADRUPLEX STABILISING AGENT | UNIVERSITY COLLEGE LONDON (GB) | 2014-04-17 | — | — | US | disclosed |
| US-20140107168-A1 | G-QUADRUPLEX STABILISING AGENT | UNIVERSITY COLLEGE LONDON (GB) | 2014-04-17 | — | — | US | disclosed |
| US-20140107168-A1 | G-QUADRUPLEX STABILISING AGENT | UNIVERSITY COLLEGE LONDON (GB) | 2014-04-17 | — | — | US | disclosed |
| EP-2694487-A1 | G-QUADRUPLEX STABILISING AGENT | University College London (GB) | 2014-02-12 | — | — | EP | disclosed |
| WO-2012136997-A1 | G-QUADRUPLEX STABILISING AGENT | UNIVERSITY COLLEGE LONDON (GB) | 2012-10-11 | — | — | WO | disclosed |
| WO-2012136997-A1 | G-QUADRUPLEX STABILISING AGENT | UNIVERSITY COLLEGE LONDON (GB) | 2012-10-11 | — | — | WO | disclosed |
| US-20100048891-A1 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG | SCHULZE KLAUSE | 2010-02-25 | — | — | US | disclosed |
| US-20100048891-A1 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG | SCHULZE KLAUSE | 2010-02-25 | — | — | US | disclosed |
| US-20100048891-A1 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG | SCHULZE KLAUSE | 2010-02-25 | — | — | US | disclosed |
| US-20070015759-A1 | Metasubstituted thiazolidinones, their manufacture and use as a drug | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | US | disclosed |
| US-20070015759-A1 | Metasubstituted thiazolidinones, their manufacture and use as a drug | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048891-A1 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG | PLK2, PDXK, PLK4 | ALDH1A1 1600/4885DDX3X 3284/4885MAPT 705/4885 |
| US-20140107168-A1 | G-QUADRUPLEX STABILISING AGENT | NR2C2, NCOR2, NR3C1 | ALDH1A1 3276/4885DDX3X 300/4885MAPT 3606/4885 |
| US-20070015759-A1 | Metasubstituted thiazolidinones, their manufacture and use as a drug | PLK4, PDXK, PLK2 | ALDH1A1 997/4885DDX3X 3444/4885MAPT 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.