Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | DDX3X | O00571 | 2/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8392614 | 0.98 | POLB (0.65) | POLBNR4A1RAB9AALDH1A1GAA | |
| SCHEMBL7731898 | 0.95 | RAB9A (0.61) | POLBNR4A1RAB9AALDH1A1GAA | |
| Benzenemethanethiol SCHEMBL7280497 | 0.88 | HDAC3 (0.58) | POLBNR4A1RAB9AALDH1A1GAA | |
| SCHEMBL10970617 | 0.87 | RAB9A (0.85) | POLBNR4A1RAB9AALDH1A1GAA | |
| SCHEMBL629093 | 0.86 | HDAC3 (0.68) | POLBRAB9AALDH1A1DDX3XHDAC3 | |
| Hydrochloric Acid SCHEMBL8392853 | 0.85 | HDAC3 (0.66) | POLBRAB9AALDH1A1DDX3XHDAC3 | |
| SCHEMBL8657219 | 0.84 | ALDH1A1 (0.69) | POLBNR4A1RAB9AALDH1A1GAA | |
| SCHEMBL6560326 | 0.84 | DDX3X (0.67) | POLBNR4A1RAB9AALDH1A1GAA | |
| SCHEMBL3646404 | 0.84 | DDX3X (0.67) | POLBALDH1A1DDX3XHDAC3HDAC4 | |
| SCHEMBL656830 | 0.83 | HDAC3 (0.73) | RAB9AALDH1A1DDX3XHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250136576-A1 | Heterocyclic Compounds and Uses Thereof | ACEA Therapeutics, Inc. (US) | 2025-05-01 | — | — | US | disclosed |
| CN-118159533-A | Heterocyclic compounds and their use | 艾森医药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-4370212-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | King Faisal University (SA) | 2023-08-22 | — | — | US | disclosed |
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287783-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | ACEA Therapeutics, Inc. (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-110357852-B | Benzopyrimidine compounds, preparation method and application | 中国药科大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-109796365-B | Synthetic method of dye intermediate with N-acetate structure | 中南林业科技大学 | 2021-09-14 | — | — | CN | disclosed |
| EP-3705477-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | Vertex Pharmaceuticals Incorporated (US) | 2020-09-09 | — | — | EP | disclosed |
| CN-107635553-B | Pyrimidine derivatives as kinase inhibitors and their therapeutic use | 常山凯捷健生物药物研发（河北）有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4118232-A | Photographic material containing sulphonic acid group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1978-10-03 | — | — | US | disclosed |
| US-4051123-A | Sulfonic-acid-group containing disazo dyestuffs | CIBA-GEIGY AG (CH) | 1977-09-27 | — | — | US | disclosed |
| US-4039316-A | 3-Methoxy crotonanilides as herbicides | ROUSSEL UCLAF (FR) | 1977-08-02 | — | — | US | disclosed |
| US-4028093-A | Meta-bis anilide derivatives and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4022763-A | Sulfaphenyl-azo-phenyl-azo-aminophenyl dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |
| US-3979202-A | Meta-bifunctional benzenes and herbicidal compositions | MONSANTO COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3957860-A | SULFAMIC ACID | CIBA-GEIGY AG (CH) | 1976-05-18 | — | — | US | disclosed |
| US-3941581-A | Meta-bis anilide derivatives and their utility as herbicides | STAUFFER CHEMICAL COMPANY (US) | 1976-03-02 | — | — | US | disclosed |
| US-3937729-A | META-BIS ANILIDE DERIVATIVES AND THEIR UTILITY AS HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731980-B1 | Furo[3,4-b]quinolone compounds as antibacterial agents | TOP2A, TOP2B, TOP1 | POLB 4/4885NR4A1 289/4885RAB9A 895/4885 |
| US-20250136576-A1 | Heterocyclic Compounds and Uses Thereof | CHEK2, CDK2, CDK1 | POLB 1485/4885NR4A1 3932/4885RAB9A 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.