Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321442 | 0.93 | MEN1 (0.45) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL1033018 | 0.89 | KDM5A (0.53) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL321280 | 0.82 | USP2 (0.44) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL322013 | 0.80 | CA12 (0.41) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL1033282 | 0.78 | GRIN2D (0.43) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL321963 | 0.76 | KDM5A (0.54) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7754979 | 0.75 | KDM5A (0.53) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7754982 | 0.74 | KDM5A (0.52) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL7829858 | 0.72 | MAPT (0.48) | POLBMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL321856 | 0.72 | KDM5A (0.44) | MEN1KMT2APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590949-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | Active Biotech AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |