Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321280 | 0.87 | USP2 (0.44) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL1033018 | 0.85 | KDM5A (0.53) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL1033282 | 0.82 | GRIN2D (0.43) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL321442 | 0.81 | MEN1 (0.45) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL321959 | 0.80 | MEN1 (0.43) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7558468 | 0.73 | GPBAR1 (0.38) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL7557817 | 0.73 | GPBAR1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7818937 | 0.73 | PTGS2 (0.44) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL322275 | 0.71 | USP2 (0.44) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7829858 | 0.70 | MAPT (0.48) | MAPTSMN1; SMN2POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590949-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | Active Biotech AB (SE) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004338-A1 | METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES | ACTIVE BIOTECH AB (SE) | 2012-01-12 | — | — | WO | disclosed |