Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 7/20 | 0.43 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3216577 | 0.85 | RORC (0.50) | RORCP2RX1TMPRSS4MAPTSMN1; SMN2 | |
| SCHEMBL3212463 | 0.84 | RORC (0.48) | RORCP2RX1TMPRSS4MAPTSMN1; SMN2 | |
| SCHEMBL1842685 | 0.80 | ALDH1A1 (0.57) | MAPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL1275444 | 0.79 | KCNMA1 (0.45) | RORCP2RX1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL1844350 | 0.79 | KCNMA1 (0.51) | RORCP2RX1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3224798 | 0.79 | RORC (0.37) | RORCP2RX1TMPRSS4MAPTSMN1; SMN2 | |
| SCHEMBL3211887 | 0.79 | IRAK4 (0.49) | MAPTSMN1; SMN2NPC1RAB9AWDR5 | |
| SCHEMBL27785087 | 0.79 | MEN1 (0.50) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5834661 | 0.78 | RORC (0.63) | RORCMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30868357 | 0.76 | P2RX1 (0.62) | RORCP2RX1TMPRSS4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| CN-101489990-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044006-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008000438-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008000438-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | RORC 4604/4885P2RX1 344/4885TMPRSS4 4319/4885 |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | RORC 4599/4885P2RX1 341/4885TMPRSS4 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.