Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL5827555 | 0.91 | ALDH1A1 (0.47) | ATML3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL5827554 | 0.88 | TDP1 (0.42) | ATML3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL3212278 | 0.83 | ATM (0.72) | ATML3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL2090976 | 0.76 | MAOB (0.62) | L3MBTL1MAPTALDH1A1LMNAALOX12 | |
| SCHEMBL18623122 | 0.76 | MAOB (0.62) | L3MBTL1MAPTALDH1A1LMNAALOX12 | |
| Diethylamine SCHEMBL3227780 | 0.75 | ALDH1A1 (0.49) | L3MBTL1MAPTALDH1A1LMNARXRA | |
| SCHEMBL3227770 | 0.75 | MAOB (0.45) | RXRASMN1; SMN2F2 | |
| SCHEMBL11301982 | 0.74 | CES2 (0.58) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9047043 | 0.73 | SRD5A2 (0.65) | ATML3MBTL1MAPTALDH1A1LMNA | |
| SCHEMBL19712578 | 0.71 | MAOB (0.55) | L3MBTL1MAPTALDH1A1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | claimed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| EP-1124791-B1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION (GB) | 2005-01-12 | — | — | EP | disclosed |
| EP-1124791-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026180-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | ATM 1852/4885L3MBTL1 656/4885MAPT 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.