Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827554 | 0.91 | TDP1 (0.42) | MAOBAPPKMT2ANOX1RXRA | |
| SCHEMBL3227881 | 0.84 | SRD5A2 (0.61) | MAOBNR4A2KMT2ASRD5A2NOX1 | |
| SCHEMBL10592238 | 0.82 | BCHE (0.61) | MAOBBCHEAPPNR4A2NOX1 | |
| Diethylamine SCHEMBL3227780 | 0.78 | ALDH1A1 (0.49) | MAOBBCHEAPPNR4A2KMT2A | |
| SCHEMBL6715345 | 0.77 | ALDH1A1 (0.46) | MAOBKMT2ANOX1TSHRSMN1; SMN2 | |
| SCHEMBL1886413 | 0.76 | TSHR (0.37) | KMT2ANOX1TSHR | |
| SCHEMBL11670600 | 0.76 | MAOB (0.56) | MAOBBCHENR4A2KMT2ASRD5A2 | |
| SCHEMBL3221879 | 0.75 | ATM (0.50) | F2RXRASMN1; SMN2 | |
| SCHEMBL10592227 | 0.74 | BCHE (0.54) | MAOBBCHENOX1TSHRSMN1; SMN2 | |
| SCHEMBL11677532 | 0.73 | BCHE (0.53) | MAOBBCHEAPPNOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | claimed |
| US-7034129-B2 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | ISIS INNOVATION LIMITED (GB) | 2006-04-25 | — | — | US | claimed |
| US-8530212-B2 | Carbene precursor compound for producing an adhesive surface on a substrate | ISIS INNOVATION LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2010-03-18 | — | — | US | disclosed |
| EP-2054465-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008023170-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ISIS INNOVATION LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |
| EP-1124791-B1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION (GB) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068783-A1 | TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION | ITGB2, ITGA2B, ITGB1 | MAOB 37/4885BCHE 925/4885APP 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.