Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227770 | 0.91 | MAOB (0.45) | SMN1; SMN2MAOBNOX1RXRAKMT2A | |
| SCHEMBL3221879 | 0.88 | ATM (0.50) | TDP1ATMNPC1HPGDRAB9A | |
| Diethylamine SCHEMBL5827555 | 0.84 | ALDH1A1 (0.47) | TDP1ATMNPC1HPGDRAB9A | |
| SCHEMBL3227881 | 0.77 | SRD5A2 (0.61) | ATMRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10592238 | 0.75 | BCHE (0.61) | ALDH1A1MAOBNOX1APP | |
| SCHEMBL3212278 | 0.73 | ATM (0.72) | TDP1ATMNPC1HPGDRAB9A | |
| Diethylamine SCHEMBL3227780 | 0.71 | ALDH1A1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6715345 | 0.70 | ALDH1A1 (0.46) | TDP1ATMNPC1HPGDRAB9A | |
| SCHEMBL11670600 | 0.69 | MAOB (0.56) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1886413 | 0.69 | TSHR (0.37) | TDP1ALDH1A1LMNANOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034129-B2 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | ISIS INNOVATION LIMITED (GB) | 2006-04-25 | — | — | US | disclosed |
| EP-1124791-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026180-A1 | SURFACE FUNCTIONALISATION | ISIS INNOVATION LIMITED (GB) | 2000-05-11 | — | — | WO | disclosed |