Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322275 | 0.88 | USP2 (0.44) | KDM4EALDH1A1GAAGRIN2DGRIN3B | |
| SCHEMBL7754982 | 0.84 | KDM5A (0.52) | KDM4EALDH1A1POLBGAATDP1 | |
| SCHEMBL1033282 | 0.80 | GRIN2D (0.43) | KDM4EPOLBTDP1GRIN2DGRIN3B | |
| SCHEMBL7556725 | 0.79 | KMT2A (0.43) | KDM4EALDH1A1GAATDP1HSD17B10 | |
| SCHEMBL2483507 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1TDP1HSD17B10KMT2A | |
| SCHEMBL7861633 | 0.77 | KDM4E (0.37) | KDM4ETDP1GRIK1GRIA1GRIA2 | |
| SCHEMBL3979257 | 0.76 | CA12 (0.51) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL6204567 | 0.75 | HDAC4 (0.49) | ALDH1A1ARMAPT | |
| SCHEMBL14335694 | 0.75 | CYP19A1 (0.42) | KDM4EALDH1A1POLBGAATDP1 | |
| SCHEMBL7559768 | 0.75 | MAPT (0.48) | KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095021-A1 | QUINOLINE DERIVATIVES | Active Biotech AB (SE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000003991-A1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2000-01-27 | — | — | WO | disclosed |