Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223315 | 1.00 | ALDH1A1 (0.49) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3209742 | 0.88 | KMT2A (0.47) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3209739 | 0.88 | KMT2A (0.47) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL13490249 | 0.86 | TRPM8 (0.39) | ALDH1A1MEN1KMT2AMAPTTAS1R3 | |
| SCHEMBL4165961 | 0.84 | MEN1 (0.49) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL4165971 | 0.84 | MEN1 (0.49) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3221983 | 0.83 | ALDH1A1 (0.55) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3221992 | 0.83 | ALDH1A1 (0.55) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3219313 | 0.83 | MEN1 (0.52) | ALDH1A1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL3219310 | 0.83 | MEN1 (0.52) | ALDH1A1EPHX2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | claimed |
| US-20100048699-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048699-A1 | CHEMICAL COMPOUNDS | ACHE, TYR, SGMS1 | ALDH1A1 128/4885EPHX2 727/4885MEN1 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.