Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209071 | 0.95 | CYP1A2 (0.39) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL7217044 | 0.87 | LMNA (0.42) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL3230360 | 0.86 | HSP90AA1 (0.36) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL268986 | 0.84 | LMNA (0.36) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL28638598 | 0.84 | LMNA (0.40) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL13492209 | 0.82 | LMNA (0.35) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL3363792 | 0.82 | CYP3A4 (0.36) | CYP3A4CYP1A2CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL24431768 | 0.82 | ALDH1A1 (0.39) | CYP3A4LMNAALDH1A1MAPK1TSHR | |
| SCHEMBL17831410 | 0.82 | LMNA (0.39) | CYP3A4CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL7097913 | 0.82 | LMNA (0.39) | CYP3A4CYP1A2CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| EP-1833818-A1 | 6-(1H-PYRAZOL-5-YL)-1,3,5-TRIAZINE DERIVATIVES AND THEIR USE AS PROTECTIVE AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2007-09-19 | — | — | EP | claimed |
| WO-2006064366-A1 | 6- (1H-PYRAZOL-5-YL)-1, 3, 5-TRIAZINE DERIVATIVES AND THEIR USE AS PROTECTIVE AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-06-22 | — | — | WO | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | disclosed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | disclosed |
| EP-1833818-A1 | 6-(1H-PYRAZOL-5-YL)-1,3,5-TRIAZINE DERIVATIVES AND THEIR USE AS PROTECTIVE AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006064366-A1 | 6- (1H-PYRAZOL-5-YL)-1, 3, 5-TRIAZINE DERIVATIVES AND THEIR USE AS PROTECTIVE AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | CYP3A4 202/4885CYP1A2 21/4885CYP2D6 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.