SCHEMBL268986

SCHEMBL268986

CCCCC(CC)COc1ccc(-c2nc(-c3ccc(OCC(CC)CCCC)cc3O)nc(-c3cccn3C)n2)c(O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.36
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35
ALDH1A1 P00352 7/20 0.34
CYP3A4 P08684 2/20 0.34
CA2 P00918 1/20 0.34
MAPK1 P28482 3/20 0.34
TSHR P16473 2/20 0.34
HRH3 Q9Y5N1 2/20 0.32
MAPT P10636 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
NPC1 O15118 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13492209 0.98 LMNA (0.35) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL1551245 0.94 LMNA (0.33) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL1704092 0.93 LMNA (0.35) LMNAPSEN1PSEN2APH1BNCSTN
SCHEMBL7217044 0.87 LMNA (0.42) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL3226436 0.85 LMNA (0.35) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL3223605 0.84 CYP3A4 (0.42) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL28638598 0.84 LMNA (0.40) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL6705841 0.82 GPR88 (0.35) LMNAALDH1A1HRH3MAPTTDP1
SCHEMBL3468877 0.82 ALDH1A1 (0.33) LMNAALDH1A1CYP3A4CA2MAPK1
SCHEMBL29120353 0.82 LMNA (0.42) LMNAALDH1A1CYP3A4CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1077 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 US claimed
EP-2945601-B1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A LIPOPHILIC BENZOTRIAZOLE UV-SCREENING AGENT AND/OR A BIS-RESORCINYL TRIAZINE COMPOUND OREAL (FR) 2018-08-22 EP claimed
EP-2959885-A1 STABLE COSMETIC AND DERMATOLOGICAL PREPARATION WITH HIGH SUN BLOCK FACTOR Beiersdorf AG (DE) 2015-12-30 EP claimed
EP-2945601-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A LIPOPHILIC BENZOTRIAZOLE UV-SCREENING AGENT AND/OR A BIS-RESORCINYL TRIAZINE COMPOUND L'Oréal (FR) 2015-11-25 EP claimed
US-8999299-B2 Photoprotective cosmetic compositions comprising silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups and non-silicon-containing lipophilic triazine compound UV-screening agents L'OREAL (FR) 2015-04-07 US claimed
WO-2014111563-A2 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND A LIPOPHILIC BENZOTRIAZOLE UV-SCREENING AGENT AND/OR A BIS-RESORCINYL TRIAZINE COMPOUND L'OREAL (FR) 2014-07-24 WO claimed
EP-2025324-B1 Method of Quenching Electronic Excitation of Chromophore-Containing Organic Molecules in Photoactive Compositions HALLSTAR INNOVATIONS CORP (US) 2013-08-14 EP claimed
US-20120230931-A1 Sun-Care Compositions ISP INVESTMENTS LLC 2012-09-13 US claimed
EP-1216690-B1 Cosmetic and dermatological sunscreen compositions containing asymmetrically substituted triazine derivatives and citric esters surfactants BEIERSDORF AG (DE) 2012-07-25 EP claimed
EP-1649900-B1 Light screening composition comprising a derivative of dibenzoylmethane, a bis-resorcinyl triazine and a compound capable of accepting energy of the excited triplet state of dibenzoylmethane; process for photostabilisation OREAL (FR) 2012-04-18 EP claimed
EP-0998910-A1 Cosmetic and dermatologic aqueous dispersions containing triglyceridic waxes Beiersdorf Aktiengesellschaft (DE) 2000-05-10 EP claimed
WO-2000006113-A1 COSMETIC OR DERMATOLOGICAL WATER/OIL EMULSIONS CONTAINING NONIONIC SURFACTANTS AND CHARACTERIZED BY A SILICONE EMULSIFYING AGENT CONTENT BEIERSDORF AG (DE) 2000-02-10 WO claimed
EP-0976391-A1 Cosmetic and dermatological W/O emulsions, containing ionic and/or amphoteric detergents and the presence of an amount of silicone-emulgators Beiersdorf Aktiengesellschaft (DE) 2000-02-02 EP claimed
EP-0970688-A2 Use of iron, titanium mixed oxides for increasing the sun protection factor of cosmetic or dermatological sunscreens Beiersdorf Aktiengesellschaft (DE) 2000-01-12 EP claimed
EP-0963753-A2 Utilisation of C20-40 dialkyldimerate for increasing the light protection factor and/or the UV-A protection of cosmetic or dermatologic light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-12-15 EP claimed
EP-0937022-A1 PROCESS TO PREPARE A LINEAR ALDEHYDE E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1999-08-25 EP claimed
EP-0922447-A2 Utilisation of C18-38 alkylhydroxystearoylsterates for increasing the light protection factor and/or the UV-A protection of cosmetic or dermatologic light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-06-16 EP claimed
EP-0904770-A1 Utilisation of X-ray-amorphous oxids for increasing the light protectionfactor and/or the UV-protection of cosmetic or dermatologie light protection agents Beiersdorf Aktiengesellschaft (DE) 1999-03-31 EP claimed
EP-0897715-A2 Cosmetic and dermatological light protecting agents containing U.V. filtering substances as solid particles and polymeric U.V. filtering substances on silicone basis Beiersdorf Aktiengesellschaft (DE) 1999-02-24 EP claimed
WO-1998019985-A1 PROCESS TO PREPARE A LINEAR ALDEHYDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-05-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120230931-A1 Sun-Care Compositions CCNY, WIZ, SUN2 LMNA 1117/4885PSEN1 1059/4885PSEN2 1912/4885
US-20190099342-A1 COOLING PRODUCT TRPA1, TRPV2, NISCH LMNA 2013/4885PSEN1 437/4885PSEN2 332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.