Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | FBP1 | P09467 | 2/20 | 0.57 |
| ▸ | VCP | P55072 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217063 | 0.79 | NFE2L2 (0.65) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL15498134 | 0.79 | NFE2L2 (0.89) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL14880346 | 0.79 | NFE2L2 (0.69) | NFE2L2FBP1VCPCYP19A1TSHR | |
| 3-Nitrobenzaldehyde SCHEMBL54487 | 0.77 | NFE2L2 (0.67) | NFE2L2FBP1VCPCYP19A1TSHR | |
| 3-Nitrobenzaldehyde SCHEMBL29573715 | 0.77 | NFE2L2 (0.67) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL3218905 | 0.77 | APP (0.53) | FBP1CYP19A1LMNAMETAP1ALDH1A1 | |
| SCHEMBL7573955 | 0.76 | FBP1 (0.57) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL453450 | 0.76 | NFE2L2 (0.65) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL11301074 | 0.76 | CYP19A1 (0.93) | NFE2L2FBP1VCPCYP19A1TSHR | |
| SCHEMBL9727291 | 0.76 | NFE2L2 (0.65) | NFE2L2FBP1VCPCYP19A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221384-B | Benzamide derivative with anticancer activity and preparation method and application thereof | ZHEJIANG HISUN PHARM CO LTD | 2015-05-13 | — | — | CN | disclosed |
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | NFE2L2 2514/4885FBP1 493/4885VCP 4267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.