Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571662 | 0.81 | MAPT (0.56) | FBP1ALDH1A1CYP1A2KDM4EMAPT | |
| SCHEMBL11441716 | 0.77 | FBP1 (0.78) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL30781000 | 0.76 | FBP1 (0.66) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL3223970 | 0.76 | NFE2L2 (0.59) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL6771050 | 0.76 | GLO1 (0.73) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL8543768 | 0.75 | MAPT (0.70) | FBP1GLO1ALDH1A1LMNAKMT2A | |
| SCHEMBL8543761 | 0.75 | MAPT (0.70) | FBP1GLO1ALDH1A1LMNAKMT2A | |
| SCHEMBL29894113 | 0.75 | CYP1A2 (0.63) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL4943479 | 0.75 | CYP1A2 (0.63) | FBP1GLO1NFE2L2ALDH1A1LMNA | |
| SCHEMBL11361332 | 0.74 | GLO1 (0.58) | FBP1GLO1NFE2L2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |