SCHEMBL3225634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3213016	0.92	THRB (0.38)	ALDH1A1PPARGTHRBRORCHSD17B10
	SCHEMBL3221169	0.90	THRB (0.39)	ALDH1A1PPARGTHRBRORCLIPE
	SCHEMBL3217882	0.88	ALDH1A1 (0.38)	ALDH1A1PPARGTHRBRORCLIPE
	SCHEMBL3217778	0.88	RORC (0.52)	ALDH1A1PPARGTHRBRORC
	SCHEMBL3227152	0.87	POLB (0.46)	ALDH1A1PPARGLMNATSHRSMN1; SMN2
	SCHEMBL3231826	0.87	ALDH1A1 (0.37)	ALDH1A1PPARGTHRBRORCLIPE
	SCHEMBL3219867	0.87	THRB (0.40)	ALDH1A1PPARGTHRBRORCHSD17B10
	SCHEMBL3226111	0.87	THRB (0.43)	ALDH1A1PPARGTHRBRORC
	SCHEMBL3225821	0.87	THRB (0.40)	ALDH1A1PPARGTHRBRORCLIPE
	SCHEMBL3221572	0.86	POLB (0.44)	ALDH1A1PPARGLMNATSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.