SCHEMBL3225664

SCHEMBL3225664

CCC(C)(C)C=C(C)C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3225658 1.00 MAPK1 (0.31) MAPK1TDP1LMNAALOX15BLM
Ammonia Solution, Strong SCHEMBL5698791 0.98 MAPK1 (0.30) MAPK1
SCHEMBL28289216 0.83 LMNA (0.38) LMNA
SCHEMBL6726481 0.82 KDM4E (0.32) MAPK1TDP1LMNAALOX15BLM
SCHEMBL28154184 0.82 KDM4E (0.32) MAPK1TDP1LMNAALOX15BLM
SCHEMBL5690861 0.80
SCHEMBL337182 0.80 MAPK1 (0.30) MAPK1
SCHEMBL4531663 0.80 MAPK1 (0.30) MAPK1
SCHEMBL11503593 0.80 TRPA1 (0.31) MAPK1
SCHEMBL11503592 0.80 TRPA1 (0.31) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0216147-A2 Covalently crosslinked copolymer absorbent HENKEL CORPORATION (a Delaware corp.) (US) 1987-04-01 EP claimed
US-20150059238-A1 USE OF COLD FLOW IMPROVER COMPOSITIONS FOR FUELS, BLENDS THEREOF WITH BIOFUELS AND FORMULATIONS THEREOF EVONIK OIL ADDITIVES GMBH (DE) 2015-03-05 US disclosed
EP-2841538-A1 USE OF COLD FLOW IMPROVER COMPOSITIONS FOR FUELS, BLENDS THEREOF WITH BIOFUELS AND FORMULATIONS THEREOF Evonik Oil Additives GmbH (DE) 2015-03-04 EP disclosed
US-8962231-B2 Toner for magnetic single-component development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-02-24 US disclosed
US-20130344429-A1 TONER FOR MAGNETIC SINGLE-COMPONENT DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2013-12-26 US disclosed
EP-2677366-A1 Toner for magnetic single-component development Kyocera Document Solutions Inc. (JP) 2013-12-25 EP disclosed
WO-2013160228-A1 USE OF COLD FLOW IMPROVER COMPOSITIONS FOR FUELS, BLENDS THEREOF WITH BIOFUELS AND FORMULATIONS THEREOF EVONIK OIL ADDITIVES GMBH (DE) 2013-10-31 WO disclosed
US-8303943-B2 Ampholytic copolymer based on quaternized nitrogen-containing monomers BASF SE (DE) 2012-11-06 US disclosed
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2010-03-18 US disclosed
EP-2064253-B1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2009-11-18 EP disclosed
EP-0472352-B1 Sludge treatment BETZ EUROP INC (US) 1995-01-04 EP disclosed
US-5108622-A Block copolymers for sludge dewatering and a polymeric initiator for their preparation BETZ LABORATORIES, INC. (US) 1992-04-28 US disclosed
EP-0472352-A1 Sludge treatment BETZ EUROPE, INC. (US) 1992-02-26 EP disclosed
EP-0216147-A2 Covalently crosslinked copolymer absorbent HENKEL CORPORATION (a Delaware corp.) (US) 1987-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS NGLY1, NAAA, NIT2 MAPK1 1440/4885TDP1 1288/4885LMNA 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.