SCHEMBL6726481

SCHEMBL6726481

C/C(=C\C(C)(C)CN)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28154184 1.00 KDM4E (0.32) KDM4EMAPK1TDP1LMNAALOX15
SCHEMBL15846389 0.83 MAPK1 (0.33) MAPK1
SCHEMBL599525 0.82 KDM4E (0.37) KDM4E
SCHEMBL247843 0.82 KDM4E (0.37) KDM4E
SCHEMBL3225658 0.82 MAPK1 (0.31) MAPK1TDP1LMNAALOX15BLM
SCHEMBL3225664 0.82 MAPK1 (0.31) MAPK1TDP1LMNAALOX15BLM
SCHEMBL11503593 0.80 TRPA1 (0.31) MAPK1
Ammonia Solution, Strong SCHEMBL5698791 0.80 MAPK1 (0.30) MAPK1
SCHEMBL337182 0.80 MAPK1 (0.30) MAPK1
SCHEMBL4531663 0.80 MAPK1 (0.30) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040137028-A1 Transfer-free cosmetic composition comprising a dispersion of polymer particles and a specific rheological agent L'OREAL 2004-07-15 US disclosed
US-6326013-B1 TRANSFER-RESISTANT MAKE-UP L'OREAL (FR) 2001-12-04 US disclosed
US-20010006665-A1 Composition comprising at least one wax and at least one oil L'OREAL S.A. (FR) 2001-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006665-A1 Composition comprising at least one wax and at least one oil CUTA, COL14A1, LIPA KDM4E 4531/4885MAPK1 2772/4885TDP1 866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.