SCHEMBL322568

SCHEMBL322568

COC(=O)CCC(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
SLC1A1 P43005 1/20 0.46
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 3/20 0.41
CA12 O43570 3/20 0.41
CA14 Q9ULX7 3/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1308174 0.86 TSHR (0.61) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL430695 0.84 TSHR (0.58) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL30291868 0.82 TSHR (0.56) TSHRKMT2ALMNAALDH1A1L3MBTL1
SCHEMBL10626764 0.82 TSHR (0.56) TSHRKMT2ALMNAALDH1A1L3MBTL1
SCHEMBL1368882 0.82 TSHR (0.56) TSHRKMT2ALMNAALDH1A1L3MBTL1
SCHEMBL6834991 0.82 TSHR (0.56) TSHRKMT2ALMNAALDH1A1L3MBTL1
SCHEMBL25695209 0.81 TSHR (0.35) TSHRSLC1A1
SCHEMBL29151942 0.80 TSHR (0.41) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL732892 0.80 TSHR (0.57) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL8431695 0.79 TSHR (0.50) TSHRSLC1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 WO claimed
US-5072005-A Reacting acrolein, carbon monoxide, methanol in presence of palladium catalyst, hydrogen halide and arylarsine promoter NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-12-10 US claimed
WO-2025111296-A1 ELECTROLYTE COMPOSITIONS AND ELECTROCHEMICAL DEVICES USING THE SAME II-VI DELAWARE, INC. (US) 2025-05-30 WO disclosed
US-20240090312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-03-14 US disclosed
US-11744142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO disclosed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO disclosed
US-20230052017-A1 New compounds for treatment of diseases related to DUX4 expression Facio Intellectual Property B.V. (NL) 2023-02-16 US disclosed
EP-4065107-A1 NEW COMPOUNDS FOR TREATMENT OF DISEASES RELATED TO DUX4 EXPRESSION Facio Intellectual Property B.V. (NL) 2022-10-05 EP disclosed
CN-115151256-A Novel compounds for the treatment of diseases associated with DUX expression FACIO知识产权有限公司 2022-10-04 CN disclosed
CN-108368081-B Andrographolide modified compound 黑龙江珍宝岛药业股份有限公司 2021-07-09 CN disclosed
EP-1291341-A1 COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2003-03-12 EP disclosed
EP-0562819-B1 Resist coating composition JSR CORP (JP) 1999-12-01 EP disclosed
EP-0562819-A2 Resist coating composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-09-29 EP disclosed
US-5091559-A Process for the preparation of alkyl 4-oxobutyrate and its acetals QUANTUM CHEMICAL CORPORATION (US) 1992-02-25 US disclosed
US-5072005-A Reacting acrolein, carbon monoxide, methanol in presence of palladium catalyst, hydrogen halide and arylarsine promoter NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-12-10 US disclosed
US-5072005-A Reacting acrolein, carbon monoxide, methanol in presence of palladium catalyst, hydrogen halide and arylarsine promoter NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1991-12-10 US disclosed
US-4420620-A Preparation of 2-pyrrolidones NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1983-12-13 US disclosed
EP-0022626-A1 Substituted nitrodiphenyl ethers, herbicidal compositions containing them and method of combating weeds ROHM AND HAAS COMPANY (US) 1981-01-21 EP disclosed
US-3979458-A Production of unsaturated carbocyclic ketones SYNTEX CORPORATION (PM) 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744142-B2 Organic electroluminescent materials and devices TLL1, TLL2, ALPL TSHR 796/4885SLC1A1 1075/4885KMT2A 3398/4885
US-20240090312-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TLL1, TLL2, ALPL TSHR 796/4885SLC1A1 1075/4885KMT2A 3398/4885
US-20230052017-A1 New compounds for treatment of diseases related to DUX4 expression SMN1; SMN2, UTRN, DDX21 TSHR 4117/4885SLC1A1 2031/4885KMT2A 1389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.