SCHEMBL430695

SCHEMBL430695

COC(=O)CCCCC(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
L3MBTL1 Q9Y468 1/20 0.49
LMNA P02545 3/20 0.47
ALDH1A1 P00352 1/20 0.47
RECQL P46063 1/20 0.42
PABPC1 P11940 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
KMT2A Q03164 3/20 0.40
PPARG P37231 1/20 0.39
MEN1 O00255 2/20 0.39
SLC1A1 P43005 1/20 0.38
CA12 O43570 1/20 0.38
CA14 Q9ULX7 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6834991 0.98 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL30291868 0.98 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL10626764 0.98 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL1368882 0.98 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL1308174 0.93 TSHR (0.61) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL322568 0.84 TSHR (0.57) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL12504110 0.83 L3MBTL1 (0.39) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL12504186 0.83 L3MBTL1 (0.39) TSHRL3MBTL1LMNAALDH1A1PABPC1
SCHEMBL29227996 0.81 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL
SCHEMBL28085552 0.81 TSHR (0.56) TSHRL3MBTL1LMNAALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4523027-A Purification of carboxylates containing aldehydes, acetals and/or unsaturated compounds BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US claimed
EP-0101910-B1 PROCESS FOR THE PURIFICATION OF CARBOXYLIC-ACID ESTERS CONTAINING ALDEHYDES, ACETALS AND/OR UNSATURATED COMPOUNDS BASF Aktiengesellschaft (DE) 1985-04-03 EP claimed
EP-0030330-B1 PROCESS FOR PREPARING CARBOXYLIC ACID ESTERS CONTAINING ALDEHYDES AND/OR ACETALS BASF Aktiengesellschaft (DE) 1983-08-24 EP claimed
US-4350572-A Purification of carboxylic acid esters containing aldehydes and/or acetals BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US claimed
US-20220402862-A1 IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES INTELLIA THERAPEUTICS, INC. 2022-12-22 US disclosed
US-20220402862-A1 IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES INTELLIA THERAPEUTICS, INC. 2022-12-22 US disclosed
US-11420933-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2022-08-23 US disclosed
EP-4019506-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2022-06-29 EP disclosed
EP-4019506-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2022-06-29 EP disclosed
EP-3959191-A1 IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES Intellia Therapeutics, Inc. (US) 2022-03-02 EP disclosed
CN-114127044-A Ionizable amine lipids and lipid nanoparticles 英特利亚治疗股份有限公司 2022-03-01 CN disclosed
EP-3083579-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2022-01-26 EP disclosed
US-4523027-A Purification of carboxylates containing aldehydes, acetals and/or unsaturated compounds BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US disclosed
EP-0065319-B1 PROCESS FOR THE PREPARATION OF AN UNSATURATED MACROCYCLIC KETONE FIRMENICH SA (CH) 1984-10-17 EP disclosed
EP-0065319-A1 Process for the preparation of an unsaturated macrocyclic ketone FIRMENICH SA (CH) 1982-11-24 EP disclosed
US-4350572-A Purification of carboxylic acid esters containing aldehydes and/or acetals BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed
US-4346023-A FLAVORS, PERFUMES FIRMENICH SA (CH) 1982-08-24 US disclosed
US-4302607-A CYCLOPENTADECANONES FIRMENICH SA (CH) 1981-11-24 US disclosed
EP-0015412-A2 Unsaturated macrocyclic ketones; their preparation; preparation of saturated macrocyclic ketones; application in perfume and flavour compositions of some unsaturated macrocyclic ketones FIRMENICH SA (CH) 1980-09-17 EP disclosed
US-4138418-A Process for the preparation of ω,ω-dialkoxycarboxylic acid derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11420933-B2 Lipids and lipid compositions for the delivery of active agents LPAR1, LPAR4, LIPA TSHR 1257/4885L3MBTL1 1553/4885LMNA 316/4885
US-20220402862-A1 IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES PHOSPHO1, SGMS1, SGMS2 TSHR 2588/4885L3MBTL1 2440/4885LMNA 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.