Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793933 | 0.88 | ACMSD (0.53) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL676296 | 0.81 | ACMSD (0.42) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL3233008 | 0.78 | ACMSD (0.44) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL3243443 | 0.77 | CASP3 (0.47) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL188943 | 0.77 | MEN1 (0.55) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL10991732 | 0.77 | PSMB5 (0.47) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL5406706 | 0.77 | SIGMAR1 (0.48) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL6345485 | 0.77 | ACMSD (0.50) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL11724005 | 0.77 | ACMSD (0.46) | ACMSDPTGS2HDAC1HDAC2HDAC3 | |
| SCHEMBL1773230 | 0.77 | HTR2C (0.48) | ACMSDPTGS2HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019828-A1 | GLUCAGON RECEPTOR ANTAGONISTS | METABASIS THERAPEUTICS, INC. (US) | 2010-02-18 | — | — | WO | claimed |
| WO-2010019828-A1 | GLUCAGON RECEPTOR ANTAGONISTS | METABASIS THERAPEUTICS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |