Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257261 | 0.98 | CASP3 (0.46) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL362370 | 0.93 | ACMSD (0.44) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL10793933 | 0.88 | ACMSD (0.53) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL1257281 | 0.82 | CASP3 (0.47) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL13221420 | 0.80 | MAPK14 (0.40) | CASP3SENP8SENP7SENP6PTGS2 | |
| SCHEMBL17070223 | 0.80 | CASP3 (0.46) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL1257285 | 0.79 | ACMSD (0.49) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL16978437 | 0.78 | ACMSD (0.45) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL11034153 | 0.78 | CHRNB4 (0.49) | CASP3SENP8SENP7SENP6ACMSD | |
| SCHEMBL188943 | 0.77 | MEN1 (0.55) | ACMSDPTGS2HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | claimed |
| EP-0014840-B1 | FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS | MERCK PATENT GmbH (DE) | 1982-01-06 | — | — | EP | claimed |
| EP-0014840-A1 | Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | claimed |
| JP-6306361-A | — | — | None | — | — | JP | disclosed |
| WO-2024182597-A1 | VISIBLE LIGHT DRIVEN CO2 VALORIZATION | The Board of Regents for the Oklahoma Agricultural and Mechanical Colleges (US) | 2024-09-06 | — | — | WO | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458155-B2 | Pyrido[4,3-b]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. | 2015-02-19 | — | — | US | disclosed |
| US-8906925-B2 | Pyrido[4,3-B]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906925-B2 | Pyrido[4,3-B]indoles containing rigid moieties | MEDIVATION TECHNOLOGIES, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| EP-1780193-B1 | LIQUID CRYSTAL MATERIAL, METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL AND LIQUID CRYSTAL DEVICE | JAPAN SCIENCE & TECH AGENCY (JP) | 2010-05-19 | — | — | EP | disclosed |
| WO-2010051501-A1 | PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES | MEDIVATION TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | WO | disclosed |
| JP-2009138204-A | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH | 2009-06-25 | — | — | JP | disclosed |
| JP-2005113152-A | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH | 2005-04-28 | — | — | JP | disclosed |
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | disclosed |
| US-6689291-B1 | MIXTURE OF POLAR COMPOUNDS HAVING POSITIVE DIELECTRIC ANISOTROPY, COMPRISING AT LEAST ONE FLUOROPHENYLCYCLOHEXENE DERIVATIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2004-02-10 | — | — | US | disclosed |
| JP-H06306361-A | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH | 1994-11-01 | — | — | JP | disclosed |
| EP-0014840-B1 | FLUORPHENYL-TRANS-CYCLOHEXANES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTROOPTICAL DISPLAYING MEANS | MERCK PATENT GmbH (DE) | 1982-01-06 | — | — | EP | disclosed |
| EP-0014840-A1 | Fluorphenyl-trans-cyclohexanes, process for their preparation, liquid crystalline dielectrics containing them and electrooptical displaying means | MERCK PATENT GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051218-A1 | PYRIDO[4,3-B]INDOLES CONTAINING RIGID MOIETIES | HTR3B, HTR3D, HTR3A | CASP3 345/4885SENP8 4709/4885SENP7 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.