Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL3893557 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRKMT2ACHRM2 | |
| Isopropyl Alcohol SCHEMBL18984957 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRKMT2ACHRM2 | |
| Isopropyl Alcohol SCHEMBL28231979 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRKMT2ACHRM2 | |
| SCHEMBL8186085 | 0.83 | TSHR (0.44) | ALDH1A1LMNATSHRKMT2ACHRM2 | |
| Cyclohexane SCHEMBL8471239 | 0.83 | ADH1C (0.32) | ALDH1A1KMT2A | |
| Isopropyl Alcohol SCHEMBL3202296 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRCHRM2CHRM4 | |
| Benzene SCHEMBL6962050 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRKMT2ACHRM2 | |
| Fluoride SCHEMBL6463523 | 0.79 | ADH1C (0.31) | KMT2A | |
| Cyclohexane SCHEMBL11847430 | 0.79 | — | — | |
| Hexane SCHEMBL1545339 | 0.79 | PLA2G1B (0.43) | ALDH1A1LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590951-B1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | PFIZER LTD (GB) | 2015-01-07 | — | — | EP | disclosed |
| US-8772293-B2 | Chemical compounds | PFIZER LIMITED (GB) | 2014-07-08 | — | — | US | disclosed |
| EP-2590951-A1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | Pfizer Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004743-A1 | BENZENESULFONAMIDES USEFUL AS SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |
| US-20120010182-A1 | Chemical Compounds | ICAGEN INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010182-A1 | Chemical Compounds | SCN1A, SCN1B, CACNA1E | ALDH1A1 557/4885LMNA 2825/4885TSHR 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.