Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL3893557 | 0.90 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNACHRM2CHRM4 | |
| Hexane SCHEMBL9806005 | 0.89 | PLA2G1B (0.39) | ALDH1A1TSHRTDP1 | |
| Isopropyl Alcohol SCHEMBL18984957 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNACHRM2CHRM4 | |
| Isopropyl Alcohol SCHEMBL28231979 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNACHRM2CHRM4 | |
| SCHEMBL8186085 | 0.83 | TSHR (0.44) | ALDH1A1TSHRLMNACHRM2CHRM4 | |
| Methylene Chloride SCHEMBL153756 | 0.83 | CYP2C9 (0.33) | ALDH1A1TDP1CYP1A2CYP2C9HPGD | |
| Methylene Chloride SCHEMBL187626 | 0.83 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C9HPGDMAPK1 | |
| Isopropyl Alcohol SCHEMBL6666765 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TSHRLMNA | |
| Cyclohexane SCHEMBL322604 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNACHRM2CHRM4 | |
| Benzene SCHEMBL6962050 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035832-A1 | Macrolides | ALPHARMA APS (DK) | 2010-02-11 | — | — | US | disclosed |
| EP-1841775-A2 | ERYTHROMYCIN DERIVATIVES AS ANTIBACTERIAL AGENTS | Alpharma APS (DK) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006074962-A2 | ERYTHROMYCIN DERIVATIVES AS ANTIBACTERIAL AGENTS | ALPHARMA APS (DK) | 2006-07-20 | — | — | WO | disclosed |
| US-6610711-B2 | 4-phenylpiperidines for the treatment of pruritic dermatoses | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| US-20030078282-A1 | Novel 4-phenylpiperidines for the treatment of pruritic dermatoses | PFIZER INC. | 2003-04-24 | — | — | US | disclosed |
| EP-0763041-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | Novartis AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032975-A1 | INDOLOCARBAZOLE DERIVATIVES FOR SENSITIZING MULTIDRUG-RESISTANT CELLS TO ANTITUMOR AGENTS | CIBA-GEIGY AG (CH) | 1995-12-07 | — | — | WO | disclosed |
| EP-0460924-A1 | Dichloroaniline compound | GLAXO GROUP LIMITED (GB) | 1991-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035832-A1 | Macrolides | MRPL21, HDAC6, MRPS27 | ALDH1A1 4350/4885TSHR 2566/4885LMNA 1388/4885 |
| US-20030078282-A1 | Novel 4-phenylpiperidines for the treatment of pruritic dermatoses | HRH2, HRH4, HRH1 | ALDH1A1 857/4885TSHR 2835/4885LMNA 4133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.