Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL3893557 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Isopropyl Alcohol SCHEMBL18984957 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Isopropyl Alcohol SCHEMBL28231979 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Toluene SCHEMBL7694570 | 0.83 | LMNA (0.48) | ALDH1A1LMNATSHRSIGMAR1ADRA2A | |
| SCHEMBL8186085 | 0.83 | TSHR (0.44) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Benzene SCHEMBL1394090 | 0.83 | KCNH2 (0.42) | ALDH1A1TSHRSIGMAR1ADRA2AKCNH2 | |
| Acetic Acid SCHEMBL9796859 | 0.82 | CHRM2 (0.41) | ALDH1A1LMNATSHRADRA2AKCNH2 | |
| Isopropyl Alcohol SCHEMBL3202296 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Cyclohexane SCHEMBL322604 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNATSHRCHRM2CHRM1 | |
| Acetic Acid SCHEMBL5903857 | 0.80 | CHRM2 (0.39) | ALDH1A1LMNATSHRADRA2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765160-B1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | UNIV RAMOT (IL) | 2003-04-16 | — | — | EP | disclosed |
| US-6096740-A | BLOCK N-METHYL-ASPARTATE | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 2000-08-01 | — | — | US | disclosed |
| EP-0765160-A4 | — | — | 1997-04-09 | — | — | EP | disclosed |
| EP-0765160-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995020958-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1995-08-10 | — | — | WO | disclosed |