Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21111324 | 1.00 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL21111320 | 1.00 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL28653303 | 0.94 | KIF11 (0.49) | KIF11DNMT1 | |
| SCHEMBL28648933 | 0.94 | KIF11 (0.49) | KIF11DNMT1 | |
| SCHEMBL14537462 | 0.88 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL21084901 | 0.87 | KIF11 (0.60) | KIF11DNMT1 | |
| SCHEMBL21084902 | 0.87 | KIF11 (0.60) | KIF11DNMT1 | |
| SCHEMBL21084899 | 0.87 | KIF11 (0.60) | KIF11DNMT1 | |
| SCHEMBL21084926 | 0.87 | KIF11 (0.60) | KIF11DNMT1 | |
| SCHEMBL21084900 | 0.87 | KIF11 (0.60) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |
| US-20100063013-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063013-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | CTSS, CTSB, CTSZ | KIF11 4198/4885DNMT1 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.