SCHEMBL3227763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3231409	0.98	POLB (0.45)	POLBSMN1; SMN2TP53CASP1KMT2A
	SCHEMBL3226082	0.88	ALDH1A1 (0.45)	POLBKMT2AALDH1A1MEN1TSHR
	SCHEMBL3223189	0.88	NPSR1 (0.41)	SMN1; SMN2TP53KMT2ATHRBALDH1A1
	SCHEMBL3213698	0.85	ALDH1A1 (0.45)	POLBSMN1; SMN2KMT2AL3MBTL1ALDH1A1
	SCHEMBL3227581	0.84	ALDH1A1 (0.42)	KMT2AALDH1A1MEN1TSHRGAA
	SCHEMBL3231744	0.84	ALDH1A1 (0.46)	POLBSMN1; SMN2KMT2AALDH1A1MEN1
	SCHEMBL3227271	0.84	ALDH1A1 (0.46)	POLBSMN1; SMN2KMT2AALDH1A1MEN1
	SCHEMBL3219335	0.81	POLB (0.52)	POLBKMT2AMEN1
	SCHEMBL3225634	0.81	ALDH1A1 (0.39)	SMN1; SMN2TP53KMT2ATHRBALDH1A1
	SCHEMBL3217882	0.80	ALDH1A1 (0.38)	KMT2ATHRBALDH1A1MEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.